HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: SYA (P40825)
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)
Gene: ALA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 983
+	Sc
		366435 HSP82_YEAST (1-705): 0: 968: 95.63		SYA_YEAST (1-983): 0: 1283: 100.00
+	Hs
		437990 HS90B_HUMAN (5-705): 0: 1022: 61.15		SYAC_HUMAN (34-981): 0: 1172: 50.10
+	Hs
		431651 HS90A_HUMAN (4-705): 0: 1013: 60.67		SYAC_HUMAN (34-981): 0: 1172: 50.10
+	Hs
		431553 HS90A_HUMAN (4-705): 0: 1013: 60.67		SYTC_HUMAN (602-900): 3.58e-84: 288: 14.47
+	Sc
		388938 HSC82_YEAST (1-705): 0: 977: 100.00		SYTC_YEAST (600-886): 2.6e-67: 241: 13.91
+	Sc
		365516 HSP82_YEAST (1-705): 0: 968: 95.63		SYTC_YEAST (600-886): 2.6e-67: 241: 13.91