HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: ATG1 (P53104)
Serine/threonine-protein kinase ATG1 (EC 2.7.11.1) (Autophagy protein 3) (Autophagy-related protein 1) (Cytoplasm to vacuole targeting protein 10)
Gene: ATG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	37453059
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 705 Sc			1 897
+	Hs
		438193 HS90B_HUMAN (5-705): 0: 1022: 61.15		KS6A1_HUMAN (2-714): 1.7e-140: 437: 17.76
+	Hs
		438190 HS90B_HUMAN (5-705): 0: 1022: 61.15		KS6A2_HUMAN (2-713): 3.98e-139: 433: 18.22
+	Hs
		431876 HS90A_HUMAN (4-705): 0: 1013: 60.67		KS6A1_HUMAN (2-714): 1.7e-140: 437: 17.76
+	Hs
		438011 HS90B_HUMAN (5-705): 0: 1022: 61.15		KS6A3_HUMAN (3-698): 1.08e-136: 427: 18.24
+	Hs
		438138 HS90B_HUMAN (5-705): 0: 1022: 61.15		ROCK1_HUMAN (4-896): 5.58e-130: 425: 14.77
+	Hs
		431873 HS90A_HUMAN (4-705): 0: 1013: 60.67		KS6A2_HUMAN (2-713): 3.98e-139: 433: 18.22
+	Hs
		431672 HS90A_HUMAN (4-705): 0: 1013: 60.67		KS6A3_HUMAN (3-698): 1.08e-136: 427: 18.24
+	Hs
		438148 HS90B_HUMAN (5-705): 0: 1022: 61.15		KCC2D_HUMAN (22-563): 1.86e-132: 407: 19.63
+	Hs
		431827 HS90A_HUMAN (4-705): 0: 1013: 60.67		KCC2D_HUMAN (22-563): 1.86e-132: 407: 19.63
+	Hs
		438631 HS90B_HUMAN (5-705): 0: 1022: 61.15		KCC2A_HUMAN (21-555): 3.38e-127: 393: 19.70
+	Hs
		438147 HS90B_HUMAN (5-705): 0: 1022: 61.15		KCC2G_HUMAN (21-468): 8.67e-109: 348: 23.66
+	Hs
		438146 HS90B_HUMAN (5-705): 0: 1022: 61.15		KCC2B_HUMAN (21-500): 1.42e-106: 345: 21.67
+	Hs
		431826 HS90A_HUMAN (4-705): 0: 1013: 60.67		KCC2G_HUMAN (21-468): 8.67e-109: 348: 23.66
+	Hs
		431825 HS90A_HUMAN (4-705): 0: 1013: 60.67		KCC2B_HUMAN (21-500): 1.42e-106: 345: 21.67
+	Hs
		438601 HS90B_HUMAN (5-705): 0: 1022: 61.15		KS6A6_HUMAN (22-343): 7.25e-91: 306: 22.32
+	Hs
		438277 HS90B_HUMAN (5-705): 0: 1022: 61.15		ULK3_HUMAN (28-326): 2.54e-52: 192: 39.47
+	Hs
		431967 HS90A_HUMAN (4-705): 0: 1013: 60.67		ULK3_HUMAN (28-326): 2.54e-52: 192: 39.47
+	Hs
		262221 HS90B_HUMAN (5-705): 0: 1022: 61.15		ULK1_HUMAN (24-275): 1.3e-42: 170: 38.10
+	Hs
		262219 HS90A_HUMAN (4-705): 0: 1013: 60.67		ULK1_HUMAN (24-275): 1.3e-42: 170: 38.10
+	Hs
		432294 HS90A_HUMAN (4-705): 0: 1013: 60.67		STK36_HUMAN (24-320): 3.15e-33: 140: 32.89