Protein: VATC1
V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)

Gene: VATC1, ATP6V1C1
Organism: Homo sapiens
Interactions: 50
UniProt ID: P21283

Gene Ontology (top 5):
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016241 - regulation of macroautophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637112

VPP1
V-type proton ATPase 116 kDa subunit a 1

3

12

High-throughput

0.839

High

637119

VPP2
V-type proton ATPase 116 kDa subunit a 2

3

12

High-throughput

0.839

High

276817

VATG1
V-type proton ATPase subunit G 1

2

4

High-throughput

0.789

High

637097

VA0D1
V-type proton ATPase subunit d 1

2

3

High-throughput

0.789

High

637117

VATH
V-type proton ATPase subunit H

2

1

High-throughput

0.789

High

341196

VATG2
V-type proton ATPase subunit G 2

2

4

High-throughput

0.737

High

637103

VPP3
V-type proton ATPase 116 kDa subunit a 3

2

12

High-throughput

0.737

High

637114

VPP4
V-type proton ATPase 116 kDa subunit a 4

2

12

High-throughput

0.737

High

637091

VATE1
V-type proton ATPase subunit E 1

1

4

High-throughput

0.691

High

583055

VATB1
V-type proton ATPase subunit B, kidney isoform

4

7

High-throughput

0.686

High

637109

VATC2
V-type proton ATPase subunit C 2

4

4

High-throughput

0.683

High

292553

RENR
Renin receptor

4

0

High-throughput

0.664

High

49505

TLDC2
TLD domain-containing protein 2

2

0

High-throughput

0.660

High

636990

VATB2
V-type proton ATPase subunit B, brain isoform

3

7

High-throughput

0.650

High

637093

VATA
V-type proton ATPase catalytic subunit A

2

10

High-throughput

0.601

High

637113

CDCA3
Cell division cycle-associated protein 3

2

0

High-throughput

0.585

High

637120

VATD
V-type proton ATPase subunit D

2

3

High-throughput

0.584

High

395488

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

637084

VATC1
V-type proton ATPase subunit C 1

1

4

High-throughput

0.541

High

637089

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.536

High

637101

PAK2
Serine/threonine-protein kinase PAK 2

1

1

High-throughput

0.536

High

637105

VATF
V-type proton ATPase subunit F

1

3

High-throughput

0.536

High

637098

ARF6
ADP-ribosylation factor 6

1

1

Small-scale

0.515

High

64935

ARRD5
Arrestin domain-containing protein 5

1

0

High-throughput

0.513

High

637096

SPSY
Spermine synthase

1

0

High-throughput

0.513

High

637104

DGUOK
Deoxyguanosine kinase, mitochondrial

1

0

High-throughput

0.513

High

637115

KTU
Protein kintoun

1

0

High-throughput

0.513

High

240740

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

637092

PPARG
Peroxisome proliferator-activated receptor gamma

1

2

High-throughput

0.479

High

536487

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

637085

OSBP1
Oxysterol-binding protein 1

1

0

High-throughput

0.458

High

637086

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

637087

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

637095

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.458

High

637099

LTOR4
Ragulator complex protein LAMTOR4

1

0

High-throughput

0.458

High

637100

TP4A2
Protein tyrosine phosphatase type IVA 2

1

0

Small-scale

0.458

High

637118

LTOR2
Ragulator complex protein LAMTOR2

1

0

High-throughput

0.458

High

637102

DDX10
Probable ATP-dependent RNA helicase DDX10

1

1

High-throughput

0.437

High

637108

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

637111

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

637107

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

637116

NUFP1
FMR1-interacting protein NUFIP1

1

0

High-throughput

0.279

Low

105324

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

587905

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

637088

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

637090

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

637094

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

637106

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

637110

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025