HitPredict - High confidence protein-protein interactions

Interactor 1: CADH2 (P15116)
Cadherin-2 (Neural cadherin) (N-cadherin) (CD antigen CD325)
Gene: Cdh2

Interactor 2: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	12695331, 15834408, 17922036
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arm~CADH_Y-type_LIR
Common GO terms	GO:0000902 - cell morphogenesis GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005912 - adherens junction and 26 others more... GO:0005916 - fascia adherens GO:0007155 - cell adhesion GO:0014704 - intercalated disc GO:0016020 - membrane GO:0016323 - basolateral plasma membrane GO:0016324 - apical plasma membrane GO:0016327 - apicolateral plasma membrane GO:0016342 - catenin complex GO:0019899 - enzyme binding GO:0019901 - protein kinase binding GO:0019903 - protein phosphatase binding GO:0030027 - lamellipodium GO:0031641 - regulation of myelination GO:0032991 - protein-containing complex GO:0034332 - adherens junction organization GO:0043410 - positive regulation of MAPK cascade GO:0044877 - protein-containing complex binding GO:0045177 - apical part of cell GO:0045202 - synapse GO:0045294 - alpha-catenin binding GO:0045296 - cadherin binding GO:0050998 - nitric-oxide synthase binding GO:0090090 - negative regulation of canonical Wnt signaling pathway GO:0097091 - synaptic vesicle clustering GO:0098609 - cell-cell adhesion GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1	906
Mm

1	781

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Last updated: 15 Jul 2024