HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization GO:0030027 - lamellipodium
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 649
+	Hs
		894060 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Ce
		136793 RAC1_CAEEL (1-192): 6e-83: 245: 79.69		UNC89_CAEEL (117-542): 8.63e-34: 141: 12.70
+	Ce
		104464 G5EBV3_CAEEL (2-192): 1.3e-77: 231: 62.30		UNC89_CAEEL (117-542): 8.63e-34: 141: 12.70
+	Hs
		925434 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		MINK1_HUMAN (185-545): 2.22e-27: 120: 13.66
+	Ce
		136794 CDC42_CAEEL (1-192): 1.77e-75: 226: 67.71		UNC89_CAEEL (117-542): 8.63e-34: 141: 12.70
+	Hs
		564611 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		MINK1_HUMAN (185-545): 2.22e-27: 120: 13.66
+	Hs
		545493 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		MINK1_HUMAN (185-545): 2.22e-27: 120: 13.66
+	Hs
		892483 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		MINK1_HUMAN (185-545): 2.22e-27: 120: 13.66
+	Hs
		297823 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		297812 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		297819 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		297827 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		925387 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11
+	Hs
		297820 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		564587 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11
+	Hs
		297809 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		K0754_HUMAN (276-647): 2.66e-15: 82.2: 12.17
+	Hs
		892450 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11