HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: ANKL2 (Q86XL3)
Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)
Gene: ANKLE2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 938
+	Hs
		892466 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		951128 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		894183 CDC42_HUMAN (1-192): 4.69e-77: 230: 68.75		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		900653 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		ANKL2_HUMAN (1-938): 0: 1602: 100.00
+	Hs
		436387 RHOC_HUMAN (5-192): 1.83e-73: 221: 54.79		ANKL2_HUMAN (1-938): 0: 1602: 100.00