Protein: BUL2
Ubiquitin ligase-binding protein BUL2

Gene: BUL2
Organism: Saccharomyces cerevisiae S288C
Interactions: 110
UniProt ID: Q03758

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0005737 - cytoplasm
GO:0006513 - protein monoubiquitination
GO:0034450 - ubiquitin-ubiquitin ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

815558

RSP5
E3 ubiquitin-protein ligase RSP5

4

3

Small-scale

0.687

High

760343

BMH2
Protein BMH2

2

2

Small-scale

0.595

High

527566

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.571

High

824535

6P21
6-phosphofructo-2-kinase 1

2

2

Small-scale

0.571

High

645519

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

709456

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

722220

XPO1
Exportin-1

1

0

High-throughput

0.513

High

1043931

UPC2
Sterol uptake control protein 2

1

0

High-throughput

0.493

High

815058

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.481

High

1043915

VPS20
Vacuolar protein sorting-associated protein 20

1

1

High-throughput

0.481

High

448790

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

439419

PDC1
Pyruvate decarboxylase isozyme 1

1

1

Small-scale

0.479

High

525010

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.479

High

579986

HSC82
ATP-dependent molecular chaperone HSC82

1

2

Small-scale

0.479

High

645773

HSP74
Heat shock protein SSA4

1

5

High-throughput

0.479

High

678449

PWP2
Periodic tryptophan protein 2

1

2

Small-scale

0.479

High

709959

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

803673

RPN1
26S proteasome regulatory subunit RPN1

1

1

Small-scale

0.479

High

844435

TCPH
T-complex protein 1 subunit eta

1

2

Small-scale

0.479

High

865056

TCPQ
T-complex protein 1 subunit theta

1

3

Small-scale

0.479

High

925020

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

1043925

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

1043937

6P22
6-phosphofructo-2-kinase 2

1

2

Small-scale

0.479

High

646080

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

753136

NIP80
Protein NIP100

1

0

High-throughput

0.460

High

796357

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

365175

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

438768

SC160
Protein SCP160

1

0

Small-scale

0.458

High

486789

CDC16
Anaphase-promoting complex subunit CDC16

1

0

Small-scale

0.458

High

637273

PWP1
Periodic tryptophan protein 1

1

0

Small-scale

0.458

High

701640

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.458

High

733677

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

748026

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

751474

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.458

High

763617

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

Small-scale

0.458

High

798296

ENP1
Essential nuclear protein 1

1

0

Small-scale

0.458

High

1040250

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

0

Small-scale

0.458

High

1043912

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

1043917

LCD1
DNA damage checkpoint protein LCD1

1

0

Small-scale

0.458

High

1043928

BMS1
Ribosome biogenesis protein BMS1

1

0

Small-scale

0.458

High

1043934

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

546108

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

819668

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

924053

JJJ1
J protein JJJ1

1

1

High-throughput

0.445

High

924243

IPI3
Pre-rRNA-processing protein IPI3

1

2

High-throughput

0.439

High

554041

TCPA
T-complex protein 1 subunit alpha

1

3

Small-scale

0.437

High

632729

DBP4
ATP-dependent RNA helicase HCA4

1

1

Small-scale

0.437

High

708051

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

740217

RPN2
26S proteasome regulatory subunit RPN2

1

1

Small-scale

0.437

High

747754

SMC1
Structural maintenance of chromosomes protein 1

1

1

Small-scale

0.437

High

793522

MAK5
ATP-dependent RNA helicase MAK5

1

1

Small-scale

0.437

High

810884

TCPG
T-complex protein 1 subunit gamma

1

2

Small-scale

0.437

High

811028

TCPD
T-complex protein 1 subunit delta

1

4

Small-scale

0.437

High

823641

TCPE
T-complex protein 1 subunit epsilon

1

4

Small-scale

0.437

High

864367

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.437

High

864900

VTC4
Vacuolar transporter chaperone complex subunit 4

1

1

Small-scale

0.437

High

1039840

UTP17
NET1-associated nuclear protein 1

1

2

Small-scale

0.437

High

1043268

HAS1
ATP-dependent RNA helicase HAS1

1

1

Small-scale

0.437

High

1043921

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

Small-scale

0.437

High

1043923

NOC4
Nucleolar complex protein 4

1

1

Small-scale

0.437

High

1043924

UTP4
U3 small nucleolar RNA-associated protein 4

1

1

Small-scale

0.437

High

1043932

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.437

High

1043933

MAK21
Ribosome biogenesis protein MAK21

1

1

Small-scale

0.437

High

1043935

UTP12
U3 small nucleolar RNA-associated protein 12

1

1

Small-scale

0.437

High

1043936

NOP56
Nucleolar protein 56

1

1

Small-scale

0.437

High

1043938

NOP58
Nucleolar protein 58

1

1

Small-scale

0.437

High

394864

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

791101

NOP4
Nucleolar protein 4

2

0

Small-scale

0.318

High

1043920

RRP5
rRNA biogenesis protein RRP5

2

0

Small-scale

0.318

High

670203

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

918810

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.279

Low

1038507

RPM2
Ribonuclease P protein component, mitochondrial

1

0

High-throughput

0.279

Low

577342

NSP1
Nucleoporin NSP1

1

0

High-throughput

0.251

Low

743878

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

804914

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

866062

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

1043918

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

1043929

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

0

High-throughput

0.251

Low

454233

LEUC
3-isopropylmalate dehydratase

1

0

Small-scale

0.249

Low

470584

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

Small-scale

0.249

Low

680022

CDC48
Cell division control protein 48

1

0

Small-scale

0.249

Low

733822

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

0

Small-scale

0.249

Low

734192

EF2
Elongation factor 2

1

0

Small-scale

0.249

Low

739752

SPT16
FACT complex subunit SPT16

1

0

Small-scale

0.249

Low

757528

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.249

Low

790342

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

Small-scale

0.249

Low

792927

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

793450

ATR
Serine/threonine-protein kinase MEC1

1

0

Small-scale

0.249

Low

807874

VPS45
Vacuolar protein sorting-associated protein 45

1

0

Small-scale

0.249

Low

811149

TCPZ
T-complex protein 1 subunit zeta

1

0

Small-scale

0.249

Low

811554

MNN1
Alpha-1,3-mannosyltransferase MNN1

1

0

Small-scale

0.249

Low

814375

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.249

Low

817085

RPN3
26S proteasome regulatory subunit RPN3

1

0

Small-scale

0.249

Low

817621

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

Small-scale

0.249

Low

825246

SEC24
Protein transport protein SEC24

1

0

Small-scale

0.249

Low

830169

NOP2
25S rRNA

1

0

Small-scale

0.249

Low

843267

KRI1
Protein KRI1

1

0

Small-scale

0.249

Low

865160

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

Small-scale

0.249

Low

917316

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.249

Low

917469

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

Small-scale

0.249

Low

918974

PESC
Pescadillo homolog

1

0

Small-scale

0.249

Low

1043913

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

1043914

TR120
Trafficking protein particle complex II-specific subunit 120

1

0

Small-scale

0.249

Low

1043916

PUF6
Pumilio homology domain family member 6

1

0

Small-scale

0.249

Low

1043919

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

Small-scale

0.249

Low

1043922

ESF1
Pre-rRNA-processing protein ESF1

1

0

Small-scale

0.249

Low

1043926

RRP44
Exosome complex exonuclease DIS3

1

0

Small-scale

0.249

Low

1043927

NOP12
Nucleolar protein 12

1

0

Small-scale

0.249

Low

1043930

RRP6
Exosome complex exonuclease RRP6

1

0

Small-scale

0.249

Low

1043939

NOP14
Nucleolar complex protein 14

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025