HitPredict

Interactor 1: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	25959826, 16713569
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 815
+	Mm
		869124 ERF3A_MOUSE (1-499): 0: 571: 98.60		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868935 ERF3B_MOUSE (1-499): 0: 550: 91.58		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		868867 EF1A2_MOUSE (70-498): 1.12e-173: 498: 37.16		ATX1_MOUSE (1-815): 0: 1271: 86.89