Protein: GRHPR
Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81)

Gene: GRHPR
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q9UBQ7

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005782 - peroxisomal matrix
GO:0005829 - cytosol
GO:0008465 - hydroxypyruvate reductase (NADH) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

243188

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

986787

PPIA
Peptidyl-prolyl cis-trans isomerase A

2

1

High-throughput

0.584

High

1327807

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.571

High

132523

CDC7
Cell division cycle 7-related protein kinase

1

8

High-throughput

0.541

High

370800

FOS
Protein c-Fos

1

4

High-throughput

0.541

High

1218285

SMBT2
Scm-like with four MBT domains protein 2

1

1

High-throughput

0.536

High

1447299

PRDM9
Histone-lysine N-methyltransferase PRDM9

1

1

High-throughput

0.536

High

1458634

S23A1
Solute carrier family 23 member 1

1

0

Small-scale

0.516

High

254446

CC14B
Dual specificity protein phosphatase CDC14B

1

3

High-throughput

0.515

High

1122872

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.513

High

178054

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

1

High-throughput

0.508

High

1395306

LCOR
Ligand-dependent corepressor

1

5

High-throughput

0.494

High

1126842

SLBP
Histone RNA hairpin-binding protein

1

0

High-throughput

0.493

High

1447301

PRDM7
Histone-lysine N-methyltransferase PRDM7

1

8

High-throughput

0.489

High

1458635

GLSL
Glutaminase liver isoform, mitochondrial

1

2

High-throughput

0.481

High

468872

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

538050

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

660745

IF4B
Eukaryotic translation initiation factor 4B

1

7

High-throughput

0.479

High

930070

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

935234

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

972094

1433E
14-3-3 protein epsilon

1

3

High-throughput

0.479

High

1220864

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1255934

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

1335033

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.479

High

1458633

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

551310

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

874203

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

0

High-throughput

0.458

High

959084

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

1438360

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

127203

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.445

High

142433

PEX7
Peroxisomal targeting signal 2 receptor

1

9

High-throughput

0.445

High

628664

CAP7
Azurocidin

1

2

High-throughput

0.445

High

1104151

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.445

High

1227627

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.445

High

1447605

ITM2C
Integral membrane protein 2C

1

2

High-throughput

0.445

High

1449903

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.445

High

353606

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

373391

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.437

High

1100488

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.437

High

598789

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

653636

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

330353

VENTX
Homeobox protein VENTX

1

6

High-throughput

0.407

High

880213

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.282

High

770435

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.279

Low

1411576

PYGO2
Pygopus homolog 2

1

0

High-throughput

0.279

Low

892734

DNLI4
DNA ligase 4

1

0

High-throughput

0.251

Low

133047

MATN2
Matrilin-2

1

0

High-throughput

0.249

Low

1250705

GDPD4
Glycerophosphodiester phosphodiesterase domain-containing protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025