HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: ERBB3 (P21860)
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-3) (Tyrosine kinase-type cell surface receptor HER3)
Gene: ERBB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 31980649, unassigned2173
Identification Methods two hybrid, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~PK_Tyr_Ser-Thr
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0010628 - positive regulation of gene expression
GO:0016323 - basolateral plasma membrane
GO:0016324 - apical plasma membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 586
Hs

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Last updated: 15 Jul 2024