HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.596

Property	Details
Experiments	32814053, 17500595
Identification Methods	validated two hybrid, two hybrid array, two hybrid pooling approach, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 3142
+	Hs
		505576 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		2805 A0A0C4DH22_HUMAN (3-524): 2.52e-119: 375: 23.06		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		792107 E41L3_HUMAN (2-466): 2.17e-114: 367: 22.83		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Mm
		102711 E41L2_MOUSE (2-577): 3.85e-120: 380: 19.56		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19
+	Mm
		103298 E41L3_MOUSE (2-522): 3.29e-115: 366: 21.48		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19