HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding and 1 others more... GO:0051017 - actin filament bundle assembly
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 793
+	Hs
		719704 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		547074 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34
+	Hs
		547250 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN2_HUMAN (3-406): 4.87e-21: 101: 16.75
+	Hs
		547271 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MYH13_HUMAN (1-698): 3.34e-21: 101: 12.00
+	Hs
		547057 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43
+	Hs
		234184 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61
+	Hs
		148355 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		547232 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		640054 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		640102 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43
+	Hs
		505542 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH1_HUMAN (1-788): 6.51e-31: 133: 10.82
+	Hs
		505569 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Hs
		148455 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		299261 FARP2_HUMAN (2-548): 8.98e-114: 365: 19.42		GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77
+	Hs
		1113853 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77
+	Hs
		1331065 E41L1_HUMAN (3-524): 3.54e-119: 375: 23.06		MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45
+	Hs
		505568 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Dm
		1001871 MERH_DROME (3-586): 1.08e-131: 400: 40.58		Q0KI67_DROME (36-649): 2.65e-11: 69.6: 15.94
+	Hs
		148997 FRMD5_HUMAN (1-345): 1.1e-114: 354: 25.28		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87