HitPredict

Interactor 1: CD44 (P15379)
CD44 antigen (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen 24) (Ly-24) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: TIAM2 (Q6ZPF3)
Rho guanine nucleotide exchange factor TIAM2 (SIF and TIAM1-like exchange factor) (T-lymphoma invasion and metastasis-inducing protein 2) (TIAM-2)
Gene: TIAM2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	19893486
Identification Methods	surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 778 Mm			1 1715
+	Mm
		548147 CD44_MOUSE (1-778): 5.15e-156: 475: 100.00		TIAM1_MOUSE (294-1660): 0: 1251: 41.58
+	Hs
		555135 CD44_HUMAN (1-778): 1.41e-146: 449: 65.77		TIAM1_HUMAN (294-1621): 0: 1218: 42.60
+	Hs
		555197 CD44_HUMAN (1-778): 1.41e-146: 449: 65.77		ECT2_HUMAN (963-1596): 2.73e-81: 291: 17.41
+	Hs
		555175 CD44_HUMAN (1-778): 1.41e-146: 449: 65.77		ARHG1_HUMAN (899-1624): 5.14e-81: 290: 14.30
+	Hs
		555209 CD44_HUMAN (1-778): 1.41e-146: 449: 65.77		ARHGC_HUMAN (995-1585): 4.79e-77: 285: 16.33
+	Hs
		555104 CD44_HUMAN (1-778): 1.41e-146: 449: 65.77		VAV2_HUMAN (1115-1472): 1.52e-61: 230: 20.11
+	Ce
		136804 UNC89_CAEEL (153-668): 3.67e-28: 124: 8.40		VAV_CAEEL (1008-1433): 7.54e-69: 255: 19.55