Protein: MYH11
Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)

Gene: MYH11
Organism: Homo sapiens
Interactions: 118
UniProt ID: P35749

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

728459

ARP3
Actin-related protein 3

1

13

High-throughput

0.691

High

728496

OVCA2
Esterase OVCA2

3

0

High-throughput

0.638

High

728458

MYL6
Myosin light polypeptide 6

2

17

High-throughput

0.628

High

728523

CING
Cingulin

1

14

High-throughput

0.618

High

159551

ML12B
Myosin regulatory light chain 12B

1

19

Small-scale

0.618

High

580616

ML12A
Myosin regulatory light chain 12A

1

19

High-throughput

0.618

High

725097

MYH10
Myosin-10

1

16

High-throughput

0.618

High

728479

TNIP1
TNFAIP3-interacting protein 1

2

18

High-throughput

0.611

High

233925

GDF9
Growth/differentiation factor 9

2

0

High-throughput

0.602

High

528682

CFTR
Cystic fibrosis transmembrane conductance regulator

2

12

High-throughput

0.601

High

728468

EM55
55 kDa erythrocyte membrane protein

2

1

High-throughput

0.574

High

728466

1433Z
14-3-3 protein zeta/delta

2

17

High-throughput

0.571

High

626064

APC
Adenomatous polyposis coli protein

1

3

High-throughput

0.541

High

728465

GRB2
Growth factor receptor-bound protein 2

1

9

High-throughput

0.541

High

128473

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.536

High

167488

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

20

High-throughput

0.536

High

181299

ARPC5
Actin-related protein 2/3 complex subunit 5

1

2

High-throughput

0.536

High

313766

SVIL
Supervillin

1

5

High-throughput

0.536

High

336393

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

597987

FLNA
Filamin-A

1

8

High-throughput

0.536

High

599624

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

3

High-throughput

0.536

High

728453

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.536

High

728455

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

728460

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

728464

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

High-throughput

0.536

High

728467

UBX2A
UBX domain-containing protein 2A

1

2

High-throughput

0.536

High

728471

1433F
14-3-3 protein eta

1

17

High-throughput

0.536

High

728472

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.536

High

728474

TRAF2
TNF receptor-associated factor 2

1

5

High-throughput

0.536

High

728477

BMPR2
Bone morphogenetic protein receptor type-2

1

1

High-throughput

0.536

High

728481

RBP1
RalA-binding protein 1

1

3

High-throughput

0.536

High

728492

POC1A
POC1 centriolar protein homolog A

1

5

High-throughput

0.536

High

728499

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.536

High

728508

PARK7
Parkinson disease protein 7

1

2

High-throughput

0.536

High

728510

ARP5L
Actin-related protein 2/3 complex subunit 5-like protein

1

2

High-throughput

0.536

High

728527

AURKC
Aurora kinase C

1

15

High-throughput

0.536

High

728526

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.518

High

728528

SMC3
Structural maintenance of chromosomes protein 3

1

4

High-throughput

0.515

High

601151

VDAC1
Voltage-dependent anion-selective channel protein 1

1

0

High-throughput

0.513

High

728493

PLBL2
Putative phospholipase B-like 2

1

0

High-throughput

0.513

High

728495

GNPI2
Glucosamine-6-phosphate isomerase 2

1

0

High-throughput

0.513

High

283134

ZFAN5
AN1-type zinc finger protein 5

1

0

High-throughput

0.493

High

440375

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.489

High

725720

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.489

High

728482

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

728504

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

1

High-throughput

0.489

High

129709

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

5

High-throughput

0.479

High

148466

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

226691

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

241465

H2B1K
Histone H2B type 1-K

1

11

High-throughput

0.479

High

260777

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.479

High

308458

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.479

High

346097

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

373794

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

High-throughput

0.479

High

417174

ENOA
Alpha-enolase

1

3

High-throughput

0.479

High

434981

SP1
Transcription factor Sp1

1

5

Small-scale

0.479

High

456514

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

6

Small-scale

0.479

High

646685

1433T
14-3-3 protein theta

1

17

High-throughput

0.479

High

666020

SHC1
SHC-transforming protein 1

1

12

High-throughput

0.479

High

683875

1433S
14-3-3 protein sigma

1

17

Small-scale

0.479

High

728454

YAP1
Transcriptional coactivator YAP1

1

7

High-throughput

0.479

High

728462

H4
Histone H4

1

4

High-throughput

0.479

High

728463

H2B1C
Histone H2B type 1-C/E/F/G/I

1

11

High-throughput

0.479

High

728470

KIF23
Kinesin-like protein KIF23

1

8

High-throughput

0.479

High

728473

TFCP2
Alpha-globin transcription factor CP2

1

3

High-throughput

0.479

High

728476

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.479

High

728480

KIF14
Kinesin-like protein KIF14

1

4

High-throughput

0.479

High

728484

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

728485

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

728488

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

12

High-throughput

0.479

High

728490

SLN11
Schlafen family member 11

1

5

Small-scale

0.479

High

728494

FBX25
F-box only protein 25

1

8

High-throughput

0.479

High

728498

H2A1C
Histone H2A type 1-C

1

1

High-throughput

0.479

High

728500

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.479

High

728501

TBC31
TBC1 domain family member 31

1

4

High-throughput

0.479

High

728502

SPDLY
Protein Spindly

1

14

High-throughput

0.479

High

728503

AURKB
Aurora kinase B

1

15

High-throughput

0.479

High

728505

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

728513

SIK2
Serine/threonine-protein kinase SIK2

1

11

Small-scale

0.479

High

728514

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

728515

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

728517

ECT2
Protein ECT2

1

8

High-throughput

0.479

High

728519

ANLN
Anillin

1

5

High-throughput

0.479

High

728524

WRP73
WD repeat-containing protein WRAP73

1

2

High-throughput

0.479

High

728525

HDAC6
Histone deacetylase 6

1

13

High-throughput

0.479

High

728461

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

728509

MYOC
Myocilin

1

0

Small-scale

0.458

High

728516

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.458

High

728520

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.458

High

728521

HYPK
Huntingtin-interacting protein K

1

0

High-throughput

0.458

High

728456

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

7

High-throughput

0.445

High

728475

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

1

High-throughput

0.445

High

728491

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.445

High

728507

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

4

High-throughput

0.445

High

329442

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.437

High

552089

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

650519

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

719828

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

728487

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

728506

RHOV
Rho-related GTP-binding protein RhoV

1

5

High-throughput

0.437

High

728512

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

3

High-throughput

0.437

High

728530

LOXL2
Lysyl oxidase homolog 2

1

3

High-throughput

0.437

High

91467

E7ERK7
TBC1 domain family member 31

1

4

High-throughput

0.407

High

401530

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

728469

TF2B
Transcription initiation factor IIB

1

1

Small-scale

0.407

High

728457

RWD2B
RWD domain-containing protein 2B

3

0

High-throughput

0.347

High

372950

C4BPA
C4b-binding protein alpha chain

1

0

High-throughput

0.279

Low

728483

ASTE1
Protein asteroid homolog 1

1

0

High-throughput

0.279

Low

728489

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

728511

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.279

Low

728518

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.279

Low

728529

SL9A8
Sodium/hydrogen exchanger 8

1

0

High-throughput

0.279

Low

61170

PDES1
Plasmanylethanolamine desaturase 1

1

0

High-throughput

0.249

Low

728478

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

728486

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

728497

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

0

High-throughput

0.249

Low

728522

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

562009

UD2B7
UDP-glucuronosyltransferase 2B7

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024