Protein: ADA10
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)

Gene: ADA10, ADAM10
Organism: Homo sapiens
Interactions: 173
UniProt ID: O14672

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001701 - in utero embryonic development
GO:0002315 - marginal zone B cell differentiation
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160959

TSN15
Tetraspanin-15

4

20

Small-scale

0.899

High

161016

TSN5
Tetraspanin-5

3

20

Small-scale

0.871

High

161015

CD81
CD81 antigen

4

20

Small-scale

0.860

High

160995

CD9
CD9 antigen

3

20

Small-scale

0.830

High

161061

TSN14
Tetraspanin-14

2

20

Small-scale

0.811

High

161054

TSN33
Tetraspanin-33

2

20

Small-scale

0.776

High

161008

CD151
CD151 antigen

2

20

Small-scale

0.712

High

161099

FPRP
Prostaglandin F2 receptor negative regulator

2

3

Small-scale

0.712

High

160960

TSN12
Tetraspanin-12

1

20

Small-scale

0.691

High

161081

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

12

High-throughput

0.691

High

161083

SIRPD
Signal-regulatory protein delta

1

4

High-throughput

0.691

High

161102

BTNL2
Butyrophilin-like protein 2

1

7

High-throughput

0.691

High

161105

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

12

High-throughput

0.691

High

161074

TSN17
Tetraspanin-17

1

20

Small-scale

0.665

High

161084

TSN10
Tetraspanin-10

1

20

Small-scale

0.665

High

160971

LCK
Tyrosine-protein kinase Lck

2

20

Small-scale

0.634

High

161018

GRB2
Growth factor receptor-bound protein 2

2

20

Small-scale

0.634

High

161042

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.602

High

161041

HFE
Hereditary hemochromatosis protein

2

15

High-throughput

0.601

High

161044

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

18

High-throughput

0.601

High

161055

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

2

6

High-throughput

0.601

High

161104

FBX2
F-box only protein 2

2

12

High-throughput

0.601

High

161025

DLG1
Disks large homolog 1

2

11

Small-scale

0.595

High

160955

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.575

High

160957

TSN9
Tetraspanin-9

1

20

High-throughput

0.575

High

160966

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.575

High

160969

ITB1
Integrin beta-1

1

14

High-throughput

0.575

High

160978

CD63
CD63 antigen

1

20

High-throughput

0.575

High

161001

CD82
CD82 antigen

1

20

High-throughput

0.575

High

161011

BCAM
Basal cell adhesion molecule

1

5

High-throughput

0.575

High

161069

IGSF8
Immunoglobulin superfamily member 8

1

2

High-throughput

0.575

High

160983

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

2

High-throughput

0.571

High

161057

S15A3
Solute carrier family 15 member 3

2

3

High-throughput

0.571

High

161077

SH3G3
Endophilin-A3

2

20

High-throughput

0.571

High

161093

FBX6
F-box only protein 6

2

12

High-throughput

0.571

High

160956

GRAP2
GRB2-related adapter protein 2

1

20

Small-scale

0.561

High

160962

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.561

High

160986

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.561

High

161075

SNX18
Sorting nexin-18

1

19

Small-scale

0.561

High

161076

SH3G1
Endophilin-A2

1

20

Small-scale

0.561

High

161106

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

20

Small-scale

0.561

High

161038

TAZ
Tafazzin

2

3

High-throughput

0.558

High

161064

CTL1
Choline transporter-like protein 1

2

1

High-throughput

0.552

High

160984

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.547

High

160950

EXTL3
Exostosin-like 3

1

1

High-throughput

0.536

High

160958

ECEL1
Endothelin-converting enzyme-like 1

1

3

High-throughput

0.536

High

160961

B3GT4
Beta-1,3-galactosyltransferase 4

1

3

High-throughput

0.536

High

160980

LYAG
Lysosomal alpha-glucosidase

1

1

High-throughput

0.536

High

160987

PRG2
Bone marrow proteoglycan

1

14

High-throughput

0.536

High

160991

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

1

15

High-throughput

0.536

High

160994

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

12

High-throughput

0.536

High

160997

PRTN3
Myeloblastin

1

20

High-throughput

0.536

High

161002

CALX
Calnexin

1

17

High-throughput

0.536

High

161004

PDIA3
Protein disulfide-isomerase A3

1

5

Small-scale

0.536

High

161013

TMPS3
Transmembrane protease serine 3

1

19

High-throughput

0.536

High

161020

IL5RA
Interleukin-5 receptor subunit alpha

1

6

High-throughput

0.536

High

161027

KLRD1
Natural killer cells antigen CD94

1

20

High-throughput

0.536

High

161039

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

4

High-throughput

0.536

High

161047

BRID5
BRICHOS domain-containing protein 5

1

2

High-throughput

0.536

High

161053

TM11B
Transmembrane protease serine 11B

1

18

High-throughput

0.536

High

161066

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.536

High

161070

T106A
Transmembrane protein 106A

1

7

High-throughput

0.536

High

161073

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.536

High

161080

TMPSD
Transmembrane protease serine 13

1

19

High-throughput

0.536

High

161082

CNTP3
Contactin-associated protein-like 3

1

13

High-throughput

0.536

High

161086

UD17
UDP-glucuronosyltransferase 1A7

1

1

High-throughput

0.536

High

161087

CRLF2
Cytokine receptor-like factor 2

1

2

High-throughput

0.536

High

161089

SDF2L
Stromal cell-derived factor 2-like protein 1

1

7

High-throughput

0.536

High

161100

DNJB9
DnaJ homolog subfamily B member 9

1

3

High-throughput

0.536

High

161108

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

3

High-throughput

0.536

High

161111

ST14
Suppressor of tumorigenicity 14 protein

1

18

High-throughput

0.536

High

160947

TMPS2
Transmembrane protease serine 2

1

19

High-throughput

0.515

High

160968

A4
Amyloid-beta precursor protein

1

9

High-throughput

0.515

High

161021

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

67581

RHG32
Rho GTPase-activating protein 32

1

1

Small-scale

0.501

High

156397

RHG33
Rho GTPase-activating protein 33

1

1

Small-scale

0.501

High

160944

CSKP
Peripheral plasma membrane protein CASK

1

17

Small-scale

0.501

High

160946

RIMB2
RIMS-binding protein 2

1

11

Small-scale

0.501

High

160952

VINEX
Vinexin

1

18

Small-scale

0.501

High

160954

GAS7
Growth arrest-specific protein 7

1

17

Small-scale

0.501

High

160964

SPTA1
Spectrin alpha chain, erythrocytic 1

1

3

Small-scale

0.501

High

160988

HCLS1
Hematopoietic lineage cell-specific protein

1

19

Small-scale

0.501

High

161007

CRK
Adapter molecule crk

1

12

Small-scale

0.501

High

161026

MYO1E
Unconventional myosin-Ie

1

3

Small-scale

0.501

High

161030

MYO7A
Unconventional myosin-VIIa

1

1

Small-scale

0.501

High

161033

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

Small-scale

0.501

High

161035

LASP1
LIM and SH3 domain protein 1

1

20

Small-scale

0.501

High

161043

SH319
SH3 domain-containing protein 19

1

20

Small-scale

0.501

High

161058

DOCK4
Dedicator of cytokinesis protein 4

1

5

Small-scale

0.501

High

161060

NGEF
Ephexin-1

1

7

Small-scale

0.501

High

161067

DOCK2
Dedicator of cytokinesis protein 2

1

2

Small-scale

0.501

High

161068

PEX13
Peroxisomal membrane protein PEX13

1

14

Small-scale

0.501

High

161085

ZDHC6
Palmitoyltransferase ZDHHC6

1

2

Small-scale

0.501

High

161096

ARH38
Rho guanine nucleotide exchange factor 38

1

5

Small-scale

0.501

High

161101

RIM3A
RIMS-binding protein 3A

1

12

Small-scale

0.501

High

161103

DBNL
Drebrin-like protein

1

20

Small-scale

0.501

High

160970

INSR
Insulin receptor

1

16

High-throughput

0.500

High

160975

IGF1R
Insulin-like growth factor 1 receptor

1

14

High-throughput

0.500

High

161037

NTRK3
NT-3 growth factor receptor

1

13

High-throughput

0.500

High

160985

PSPC
Surfactant protein C

1

4

High-throughput

0.489

High

161029

SG2A2
Mammaglobin-A

1

3

High-throughput

0.489

High

161040

CL12B
C-type lectin domain family 12 member B

1

20

High-throughput

0.489

High

161071

SPSB4
SPRY domain-containing SOCS box protein 4

1

8

High-throughput

0.489

High

161078

RUSC1
AP-4 complex accessory subunit RUSC1

1

0

Small-scale

0.480

High

160948

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

160949

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

19

Small-scale

0.479

High

160963

EGFR
Epidermal growth factor receptor

1

17

High-throughput

0.479

High

160972

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.479

High

160973

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.479

High

160974

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

12

High-throughput

0.479

High

160977

HCK
Tyrosine-protein kinase HCK

1

20

Small-scale

0.479

High

160981

ANDR
Androgen receptor

1

3

Small-scale

0.479

High

160989

NCF1
Neutrophil cytosol factor 1

1

20

Small-scale

0.479

High

160992

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

160993

NCK1
SH2/SH3 adapter protein NCK1

1

20

Small-scale

0.479

High

160999

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

161000

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

161003

EPHA3
Ephrin type-A receptor 3

1

17

Small-scale

0.479

High

161005

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

161006

PHB1
Prohibitin 1

1

4

High-throughput

0.479

High

161009

PAXI
Paxillin

1

4

Small-scale

0.479

High

161012

BACE1
Beta-secretase 1

1

1

Small-scale

0.479

High

161019

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

161023

ITK
Tyrosine-protein kinase ITK/TSK

1

20

Small-scale

0.479

High

161028

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

4

Small-scale

0.479

High

161031

GRAP
GRB2-related adapter protein

1

20

Small-scale

0.479

High

161032

CUL3
Cullin-3

1

8

High-throughput

0.479

High

161049

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

161052

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

161062

SNX33
Sorting nexin-33

1

20

Small-scale

0.479

High

161079

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

19

Small-scale

0.479

High

161095

T106B
Transmembrane protein 106B

1

7

High-throughput

0.479

High

161097

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

3

High-throughput

0.479

High

161107

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

19

Small-scale

0.479

High

161110

SNX9
Sorting nexin-9

1

20

Small-scale

0.479

High

160951

EFNA2
Ephrin-A2

1

0

Small-scale

0.458

High

160990

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

161094

HEBP1
Heme-binding protein 1

1

0

High-throughput

0.458

High

62300

SH321
SH3 domain-containing protein 21

1

20

Small-scale

0.457

High

161046

ARHGG
Rho guanine nucleotide exchange factor 16

1

8

Small-scale

0.457

High

161056

ARHGJ
Rho guanine nucleotide exchange factor 19

1

7

Small-scale

0.457

High

161091

ARHG4
Rho guanine nucleotide exchange factor 4

1

6

Small-scale

0.457

High

161092

OTOR
Otoraplin

1

1

Small-scale

0.457

High

104060

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.445

High

160953

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

160976

4F2
Amino acid transporter heavy chain SLC3A2

1

2

High-throughput

0.445

High

160979

PGFRB
Platelet-derived growth factor receptor beta

1

10

High-throughput

0.445

High

160982

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

5

High-throughput

0.445

High

160996

ITA6
Integrin alpha-6

1

4

High-throughput

0.445

High

160998

ITA3
Integrin alpha-3

1

4

High-throughput

0.445

High

161010

MMP14
Matrix metalloproteinase-14

1

2

High-throughput

0.445

High

161014

NXPH1
Neurexophilin-1

1

1

High-throughput

0.445

High

161022

MFGM
Lactadherin

1

2

High-throughput

0.445

High

161036

S39AE
Metal cation symporter ZIP14

1

10

High-throughput

0.445

High

161048

CSPG4
Chondroitin sulfate proteoglycan 4

1

10

High-throughput

0.445

High

161059

LYPD1
Ly6/PLAUR domain-containing protein 1

1

4

High-throughput

0.445

High

161072

ESPB1
Epididymal sperm-binding protein 1

1

3

High-throughput

0.445

High

161098

TEN3
Teneurin-3

1

17

High-throughput

0.445

High

104833

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

160965

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.426

High

160967

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.426

High

161024

STX4
Syntaxin-4

1

0

High-throughput

0.426

High

161034

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

161050

ZN704
Zinc finger protein 704

1

0

High-throughput

0.426

High

161088

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

161090

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.426

High

160945

CLGN
Calmegin

1

17

High-throughput

0.407

High

161045

DIK1A
Divergent protein kinase domain 1A

1

1

High-throughput

0.407

High

161051

TBCD9
TBC1 domain family member 9

1

1

High-throughput

0.407

High

161063

CA054
Uncharacterized protein C1orf54

1

5

High-throughput

0.407

High

161065

PATE1
Prostate and testis expressed protein 1

1

4

High-throughput

0.407

High

161109

PRG3
Proteoglycan 3

1

14

High-throughput

0.407

High

161017

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025