HitPredict

Interactor 1: FOSL1 (P15407)
Fos-related antigen 1 (FRA-1)
Gene: FOSL1

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 34189442, 23661758
Identification Methods proximity labelling technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_1~bZIP_2
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
and 8 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 271
Hs

1 358
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ci
+ Ci
+ Ci
+ Hs
+ Ci
+ Hs
+ Ci
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024