HitPredict

Interactor 1: FOSL2 (P15408)
Fos-related antigen 2 (FRA-2)
Gene: FOSL2

Interactor 2: I2BPL (Q9H1B7)
Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like)
Gene: IRF2BPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 796
+	Hs
		257558 FOSL2_HUMAN (1-326): 1.44e-51: 174: 100.00		ANR17_HUMAN (62-710): 8.68e-47: 183: 11.69
+	Hs
		257539 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		ANR17_HUMAN (62-710): 8.68e-47: 183: 11.69
+	Hs
		548316 FOSL2_HUMAN (1-326): 1.44e-51: 174: 100.00		I2BP1_HUMAN (4-209): 1.68e-19: 95.3: 38.35
+	Hs
		548312 FOSL2_HUMAN (1-326): 1.44e-51: 174: 100.00		I2BP2_HUMAN (9-509): 3.36e-17: 88: 20.52
+	Hs
		345491 FOS_HUMAN (1-326): 3.85e-40: 146: 37.21		KMT2C_HUMAN (242-707): 2.59e-10: 66.8: 8.81
+	Hs
		547825 ATF2_HUMAN (4-268): 1.88e-24: 105: 18.11		I2BP1_HUMAN (4-209): 1.68e-19: 95.3: 38.35
+	Hs
		1215903 JDP2_HUMAN (61-205): 1.39e-20: 88.6: 30.07		I2BP1_HUMAN (4-209): 1.68e-19: 95.3: 38.35