Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 8900182, 9013873
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, PH~Pkinase
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0035556 - intracellular signal transduction
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 845
Hs

1 360
+ Mm
+ Hs
+ Rn

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Last updated: 15 Jul 2024