Protein: MA2B1
Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) [Cleaved into: Lysosomal alpha-mannosidase A peptide; Lysosomal alpha-mannosidase B peptide; Lysosomal alpha-mannosidase C peptide; Lysosomal alpha-mannosidase D peptide; Lysosomal alpha-mannosidase E peptide]

Gene: MA2B1, MAN2B1
Organism: Homo sapiens
Interactions: 43
UniProt ID: O00754

Gene Ontology (top 5):
GO:0004559 - alpha-mannosidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005764 - lysosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

144068

FBX6
F-box only protein 6

6

4

High-throughput

0.729

High

125072

LEG9
Galectin-9

3

2

High-throughput

0.667

High

144070

FBX2
F-box only protein 2

2

4

High-throughput

0.601

High

144033

PI15
Peptidase inhibitor 15

1

2

High-throughput

0.536

High

144034

C1QB
Complement C1q subcomponent subunit B

1

12

High-throughput

0.536

High

144039

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.536

High

144040

PRG2
Bone marrow proteoglycan

1

4

High-throughput

0.536

High

144045

CEAM8
Cell adhesion molecule CEACAM8

1

2

High-throughput

0.536

High

144048

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

1

High-throughput

0.536

High

144052

IL5RA
Interleukin-5 receptor subunit alpha

1

3

High-throughput

0.536

High

144053

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

1

High-throughput

0.536

High

144054

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

144055

LYZL1
Lysozyme-like protein 1

1

5

High-throughput

0.536

High

144059

FIBIN
Fin bud initiation factor homolog

1

3

High-throughput

0.536

High

144061

GGH
Gamma-glutamyl hydrolase

1

2

High-throughput

0.536

High

144062

ESPB1
Epididymal sperm-binding protein 1

1

2

High-throughput

0.536

High

144064

LCFC1
Sperm-egg fusion protein LLCFC1

1

2

High-throughput

0.536

High

144069

DNJB9
DnaJ homolog subfamily B member 9

1

3

High-throughput

0.536

High

144036

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.513

High

144041

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

High-throughput

0.513

High

144047

SPRE
Sepiapterin reductase

1

0

High-throughput

0.513

High

144051

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.513

High

144058

ACRBP
Acrosin-binding protein

1

0

High-throughput

0.513

High

144030

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.489

High

144035

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.489

High

144067

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.489

High

144066

NKX31
Homeobox protein Nkx-3.1

1

1

Small-scale

0.481

High

144032

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

144065

SNX27
Sorting nexin-27

1

1

High-throughput

0.479

High

144042

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

144044

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

144046

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

144057

TM192
Transmembrane protein 192

1

0

High-throughput

0.458

High

144063

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

141963

FCN1
Ficolin-1

1

2

Small-scale

0.457

High

144037

LEG1
Galectin-1

1

2

High-throughput

0.445

High

144038

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

10

High-throughput

0.445

High

144043

LEG3
Galectin-3

1

2

High-throughput

0.445

High

144050

LCN6
Epididymal-specific lipocalin-6

1

2

High-throughput

0.445

High

144060

CA054
Uncharacterized protein C1orf54

1

3

High-throughput

0.445

High

144049

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.437

High

144056

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

144031

CLGN
Calmegin

1

4

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025