HitPredict

Interactor 1: ELN (P15502)
Elastin (Tropoelastin)
Gene: ELN

Interactor 2: FBLN5 (Q9UBX5)
Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)
Gene: FBLN5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	19570982
Identification Methods	surface plasmon resonance, enzyme linked immunosorbent assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0031012 - extracellular matrix GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 448
+	Hs
		548784 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBLN2_HUMAN (28-369): 2.11e-12: 71.4: 21.91
+	Hs
		327950 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBLN4_HUMAN (3-191): 6.34e-10: 62.9: 27.18
+	Hs
		548781 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBN1_HUMAN (27-367): 4.64e-09: 61: 17.71
+	Hs
		548782 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBN2_HUMAN (7-113): 5.15e-09: 60.9: 22.43
+	Hs
		548778 ELN_HUMAN (1-786): 3.24e-43: 170: 100.00		FBLN1_HUMAN (245-332): 8.14e-09: 59.8: 32.96
+	Hs
		804242 CO4A6_HUMAN (255-783): 1.12e-30: 132: 16.85		NOTC1_HUMAN (5-391): 1.25e-18: 91.1: 13.16
+	Hs
		126331 CO1A1_HUMAN (1-458): 2.46e-20: 99.1: 17.73		MATN2_HUMAN (203-399): 5.3e-24: 107: 20.49
+	Hs
		596152 CO5A1_HUMAN (381-786): 5.16e-12: 72.1: 15.53		TENA_HUMAN (5-167): 1.5e-16: 84.5: 13.45
+	Dm
		114000 M9PB30_DROME (206-645): 2.56e-15: 83.1: 14.29		CUBN_DROME (287-405): 6.31e-12: 70.3: 15.79