Protein: MCM7
DNA replication licensing factor MCM7 (EC 3.6.4.12) (Cell division control protein 47) (Minichromosome maintenance protein 7)

Gene: MCM7
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: P38132

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

721369

MCM4
DNA replication licensing factor MCM4

21

19

Small-scale

0.987

High

664432

MCM3
DNA replication licensing factor MCM3

19

20

Small-scale

0.986

High

794096

SLD5
DNA replication complex GINS protein SLD5

15

15

Small-scale

0.983

High

794101

CDC45
Cell division control protein 45

14

15

Small-scale

0.980

High

713262

MCM5
Minichromosome maintenance protein 5

10

19

Small-scale

0.971

High

712975

MCM2
DNA replication licensing factor MCM2

8

20

Small-scale

0.961

High

794087

MCM6
DNA replication licensing factor MCM6

7

20

Small-scale

0.950

High

794079

PSF2
DNA replication complex GINS protein PSF2

5

9

Small-scale

0.912

High

794103

PSF3
DNA replication complex GINS protein PSF3

4

8

Small-scale

0.882

High

794108

PSF1
DNA replication complex GINS protein PSF1

4

11

Small-scale

0.882

High

794084

CDT1
Cell division cycle protein CDT1

3

1

Small-scale

0.861

High

794091

ORC1
Origin recognition complex subunit 1

2

20

Small-scale

0.778

High

794073

MCM7
DNA replication licensing factor MCM7

2

20

Small-scale

0.767

High

735376

MCM10
Minichromosome maintenance protein 10

8

12

Small-scale

0.744

High

794102

DIA2
Protein DIA2

5

1

Small-scale

0.718

High

794088

SLD3
DNA replication regulator SLD3

4

1

Small-scale

0.688

High

642034

DPOE
DNA polymerase epsilon catalytic subunit A

1

8

Small-scale

0.647

High

794095

CTF4
DNA polymerase alpha-binding protein

3

6

Small-scale

0.646

High

794099

CSM3
Chromosome segregation in meiosis protein 3

2

1

Small-scale

0.611

High

479261

CDC6
Cell division control protein 6

2

19

Small-scale

0.602

High

745644

ORC2
Origin recognition complex subunit 2

2

8

Small-scale

0.602

High

561308

DPOLA
DNA polymerase alpha catalytic subunit A

2

8

Small-scale

0.595

High

440929

CDC7
Cell division control protein 7

2

20

Small-scale

0.594

High

579257

HSC82
ATP-dependent molecular chaperone HSC82

2

10

High-throughput

0.584

High

794078

ATAD2
ATPase histone chaperone YTA7

2

5

Small-scale

0.584

High

794092

ORC4
Origin recognition complex subunit 4

1

19

Small-scale

0.575

High

526484

HSP72
Heat shock protein SSA2

2

12

High-throughput

0.571

High

544585

SSB1
Ribosome-associated molecular chaperone SSB1

2

14

High-throughput

0.571

High

736088

ARP2
Actin-related protein 2

1

6

High-throughput

0.536

High

739610

SPT16
FACT complex subunit SPT16

2

3

Small-scale

0.533

High

794105

SMT3
Ubiquitin-like protein SMT3

1

5

Small-scale

0.515

High

734254

DBF4
DDK kinase regulatory subunit DBF4

1

1

Small-scale

0.501

High

740568

IME2
Meiosis induction protein kinase IME2/SME1

1

14

Small-scale

0.501

High

758499

SLD2
DNA replication regulator SLD2

1

1

Small-scale

0.501

High

794083

ECO1
N-acetyltransferase ECO1

1

7

Small-scale

0.501

High

444767

SIR2
NAD-dependent histone deacetylase SIR2

1

11

Small-scale

0.481

High

794075

SHU2
Suppressor of hydroxyurea sensitivity protein 2

1

1

Small-scale

0.481

High

794080

CSM2
Chromosome segregation in meiosis protein 2

1

1

Small-scale

0.481

High

794106

PSY3
Platinum sensitivity protein 3

1

1

Small-scale

0.481

High

548768

MCM1
Pheromone receptor transcription factor

1

0

Small-scale

0.480

High

358194

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.479

High

365024

KPYK1
Pyruvate kinase 1

1

3

High-throughput

0.479

High

365605

PGK
Phosphoglycerate kinase

1

2

High-throughput

0.479

High

368435

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

392607

HSP82
ATP-dependent molecular chaperone HSP82

1

10

High-throughput

0.479

High

419706

H2A2
Histone H2A.2

1

20

High-throughput

0.479

High

435036

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

439317

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

464586

PBS2
MAP kinase kinase PBS2

1

9

High-throughput

0.479

High

586448

PCNA
Proliferating cell nuclear antigen

1

3

High-throughput

0.479

High

597440

EF3A
Elongation factor 3A

1

5

High-throughput

0.479

High

598999

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

3

High-throughput

0.479

High

626702

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.479

High

647756

RFA1
Replication factor A protein 1

1

6

High-throughput

0.479

High

677027

GID7
GID complex subunit 7

1

3

High-throughput

0.479

High

677677

MRC1
Mediator of replication checkpoint protein 1

1

1

Small-scale

0.479

High

679596

CDC48
Cell division control protein 48

1

2

Small-scale

0.479

High

688869

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.479

High

706879

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

709714

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

737833

HOG1
Mitogen-activated protein kinase HOG1

1

10

High-throughput

0.479

High

754428

NPL4
Nuclear protein localization protein 4

1

1

Small-scale

0.479

High

763875

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

776557

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.479

High

794081

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

794082

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.479

High

794085

UFD1
Ubiquitin fusion degradation protein 1

1

1

Small-scale

0.479

High

794086

VID30
GID complex subunit 1

1

5

High-throughput

0.479

High

794090

TOF1
Topoisomerase 1-associated factor 1

1

7

High-throughput

0.479

High

794093

H3
Histone H3

1

20

High-throughput

0.479

High

794100

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

794104

SCC1
Sister chromatid cohesion protein 1

1

4

High-throughput

0.479

High

794107

DBP10
ATP-dependent RNA helicase DBP10

1

11

High-throughput

0.479

High

794109

RMD5
E3 ubiquitin-protein ligase RMD5

1

1

High-throughput

0.479

High

794110

CMR1
DNA damage-binding protein CMR1

1

8

High-throughput

0.479

High

764058

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

794077

GID8
GID complex subunit 8

1

0

High-throughput

0.458

High

794097

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

726962

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

741421

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

794076

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

367949

ENO2
Enolase 2

1

3

High-throughput

0.437

High

368645

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

410081

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

794094

NUM1
Nuclear migration protein NUM1

1

14

High-throughput

0.437

High

794098

POB3
FACT complex subunit POB3

1

8

High-throughput

0.437

High

794089

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

2

0

High-throughput

0.319

High

678867

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.299

High

427563

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.249

Low

794074

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025