Protein: MCM1
Pheromone receptor transcription factor (GRM/PRTF protein)

Gene: MCM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 81
UniProt ID: P11746

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000821 - regulation of arginine metabolic process
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548765

YOX1
Homeobox protein YOX1

3

2

Small-scale

0.853

High

452768

ARGR1
Arginine metabolism regulation protein I

3

19

Small-scale

0.843

High

515405

HMAL2
Silenced mating-type protein ALPHA2

3

1

Small-scale

0.834

High

548745

MCM1
Pheromone receptor transcription factor

3

20

Small-scale

0.814

High

515401

MTAL2
Mating-type protein ALPHA2

2

1

Small-scale

0.778

High

548775

FKH2
Fork head protein homolog 2

7

3

Small-scale

0.743

High

452771

IPMK
Inositol polyphosphate multikinase

4

1

Small-scale

0.699

High

423579

ARGR2
Arginine metabolism regulation protein II

4

1

Small-scale

0.692

High

548746

STE12
Protein STE12

3

0

Small-scale

0.636

High

548799

YHP1
Homeobox protein YHP1

1

3

Small-scale

0.618

High

381823

H4
Histone H4

3

0

High-throughput

0.607

High

515392

MTAL1
Mating-type protein ALPHA1

2

0

Small-scale

0.577

High

525756

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

543608

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

548779

RSC8
Chromatin structure-remodeling complex protein RSC8

2

1

High-throughput

0.552

High

548797

RUVB1
RuvB-like protein 1

2

1

High-throughput

0.552

High

548809

RUVB2
RuvB-like protein 2

2

1

High-throughput

0.552

High

548762

BCK2
Protein BCK2

2

0

Small-scale

0.552

High

548786

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

2

0

High-throughput

0.547

High

548807

SRL2
Protein SRL2

2

0

High-throughput

0.538

High

548757

XPO1
Exportin-1

1

1

High-throughput

0.536

High

548761

RSC7
Chromatin structure-remodeling complex subunit RSC7

2

0

High-throughput

0.528

High

548790

BOP3
Protein BOP3

1

0

High-throughput

0.493

High

548770

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

1

Small-scale

0.481

High

548768

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.480

High

548784

TAF4
Transcription initiation factor TFIID subunit 4

1

0

Small-scale

0.480

High

548755

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

548785

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

548748

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

0

Small-scale

0.458

High

548749

SNF6
Transcription regulatory protein SNF6

1

0

Small-scale

0.458

High

548754

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

548764

MSN2
Zinc finger protein MSN2

1

0

High-throughput

0.458

High

548766

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

548774

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

548798

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

548800

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.458

High

548805

CDC45
Cell division control protein 45

1

0

Small-scale

0.458

High

548808

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

488906

SWI6
Regulatory protein SWI6

1

2

High-throughput

0.445

High

522864

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

548751

SWI4
Regulatory protein SWI4

1

2

High-throughput

0.445

High

548756

MCM5
Minichromosome maintenance protein 5

1

1

High-throughput

0.445

High

548758

BTAF1
TATA-binding protein-associated factor MOT1

1

9

High-throughput

0.445

High

548759

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

548760

STH1
Nuclear protein STH1/NPS1

1

10

High-throughput

0.445

High

548769

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

7

High-throughput

0.445

High

548771

SKN7
Transcription factor SKN7

1

1

High-throughput

0.445

High

548772

MBP1
Transcription factor MBP1

1

2

High-throughput

0.445

High

548777

GZF3
Protein GZF3

1

3

High-throughput

0.445

High

548781

NMD5
Nonsense-mediated mRNA decay protein 5

1

1

High-throughput

0.445

High

548787

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.445

High

548789

CBK1
Serine/threonine-protein kinase CBK1

1

1

High-throughput

0.445

High

548792

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

5

High-throughput

0.445

High

548801

ARP9
Actin-like protein ARP9

1

2

High-throughput

0.445

High

548806

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

9

High-throughput

0.445

High

548810

H2AZ
Histone H2A.Z

1

2

High-throughput

0.445

High

548788

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.438

High

394161

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

419336

H2A1
Histone H2A.1

1

0

High-throughput

0.426

High

548750

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.426

High

548752

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.426

High

548767

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.426

High

548773

POG1
Transcriptional activator POG1

1

0

High-throughput

0.426

High

548780

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

548791

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

548793

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

548794

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.426

High

548795

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

548796

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.426

High

548803

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.426

High

548804

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

548802

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

4

High-throughput

0.407

High

548753

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.249

Low

548783

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

149190

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.232

Low

548747

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

548763

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

548776

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

548778

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.232

Low

548782

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025