HitPredict

Interactor 1: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Interactor 2: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 18268104, 29054886, 29557065
Identification Methods two hybrid, affinity chromatography technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fibrillarin~Fibrillarin
Common GO terms GO:0000451 - rRNA 2'-O-methylation
GO:0000452 - snoRNA guided rRNA 2'-O-methylation
GO:0000494 - box C/D sno(s)RNA 3'-end processing
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
and 12 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 327
Sc

1 327
+ Hs
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024