HitPredict

Interactor 1: FBRL (P15646)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U3 small nucleolar RNA-associated protein NOP1) (Nucleolar protein 1) (U3 snoRNA-associated protein NOP1)
Gene: NOP1

Interactor 2: SNU13 (P39990)
13 kDa ribonucleoprotein-associated protein (Small nuclear ribonucleoprotein-associated protein 1)
Gene: SNU13

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 18268104, 29054886, 37968396, 15670595, 25888478
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Fibrillarin~Ribosomal_L7Ae
Common GO terms GO:0000452 - snoRNA guided rRNA 2'-O-methylation
GO:0000494 - box C/D sno(s)RNA 3'-end processing
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 3 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 327
Sc

1 126
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024