HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane GO:0030027 - lamellipodium
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 870
+	Hs
		942880 PABP3_HUMAN (1-636): 0: 537: 91.68		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		550401 PABP1_HUMAN (1-636): 0: 571: 100.00		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		550367 PABP1_HUMAN (1-636): 0: 571: 100.00		KMT2C_HUMAN (103-742): 7.2e-12: 71.8: 10.09
+	Hs
		550381 PABP1_HUMAN (1-636): 0: 571: 100.00		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93
+	Hs
		1102051 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		1102036 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93
+	Hs
		726745 TIA1_HUMAN (4-172): 1.85e-34: 136: 27.51		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		620230 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		620366 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		MDC1_HUMAN (56-759): 1.44e-20: 100: 8.77
+	Hs
		620504 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		PRG4_HUMAN (108-776): 1.89e-14: 80: 8.33
+	Hs
		620495 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93