HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: DUX4 (Q9UBX2)
Double homeobox protein 4 (Double homeobox protein 10)
Gene: DUX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.53	0.60	0.569

Property	Details
Experiments	26816005
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 424
+	Hs
		75595 B3KT93_HUMAN (1-636): 0: 570: 99.53		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1102123 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		1235064 Q6IQ30_HUMAN (1-635): 7.77e-178: 521: 72.29		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		95913 E7ERJ7_HUMAN (1-636): 4.97e-177: 517: 94.97		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00
+	Hs
		550172 PABP1_HUMAN (1-636): 0: 571: 100.00		LHX1_HUMAN (83-302): 1.28e-30: 123: 20.00
+	Mm
		711002 PABP1_MOUSE (1-636): 0: 570: 99.69		Q8VD35_MOUSE (1-95): 1.43e-10: 63.9: 31.58
+	Hs
		620632 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		DUX4_HUMAN (1-424): 4.08e-60: 203: 100.00