Protein: Q8VD35
Orthodenticle homeobox 2 (Otx2 protein)

Gene: Q8VD35, Otx2
Organism: Mus musculus
Interactions: 60
UniProt ID: Q8VD35

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

204351

ALX4
Homeobox protein aristaless-like 4

1

17

High-throughput

0.621

High

237263

TLX3
T-cell leukemia homeobox protein 3

1

18

High-throughput

0.621

High

1048210

EMX1
Homeobox protein EMX1

1

20

High-throughput

0.621

High

1353919

MIXL1
Homeobox protein MIXL1

1

18

High-throughput

0.621

High

236370

CRX
Cone-rod homeobox protein

1

15

Small-scale

0.618

High

629401

PO5F1
POU domain, class 5, transcription factor 1

1

20

High-throughput

0.618

High

1353905

DMBX1
Diencephalon/mesencephalon homeobox protein 1

1

17

Small-scale

0.618

High

1353918

SIX6
Homeobox protein SIX6

1

20

Small-scale

0.618

High

1000108

HXB13
Homeobox protein Hox-B13

1

20

High-throughput

0.555

High

1298585

DMRTD
Doublesex- and mab-3-related transcription factor C2

1

4

High-throughput

0.481

High

1353903

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

10

High-throughput

0.481

High

518695

EF1A1
Elongation factor 1-alpha 1

1

2

Small-scale

0.479

High

685802

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

Small-scale

0.479

High

711002

PABP1
Polyadenylate-binding protein 1

1

1

Small-scale

0.479

High

949832

PCBP1
Poly(rC)-binding protein 1

1

2

Small-scale

0.479

High

966056

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

Small-scale

0.479

High

999963

NFIX
Nuclear factor 1 X-type

1

20

Small-scale

0.479

High

1210649

LC7L3
Luc7-like protein 3

1

3

Small-scale

0.479

High

1221429

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

3

Small-scale

0.479

High

1222078

RBBP4
Histone-binding protein RBBP4

1

3

Small-scale

0.479

High

1222197

LAP2B
Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma

1

1

Small-scale

0.479

High

1222879

ERR2
Steroid hormone receptor ERR2

1

6

Small-scale

0.479

High

1222961

EWS
RNA-binding protein EWS

1

8

Small-scale

0.479

High

1229981

ZN512
Zinc finger protein 512

1

9

Small-scale

0.479

High

1230049

CDC5L
Cell division cycle 5-like protein

1

2

Small-scale

0.479

High

1296640

CGBP1
CGG triplet repeat-binding protein 1

1

1

Small-scale

0.479

High

1296687

ZN787
Zinc finger protein 787

1

5

Small-scale

0.479

High

1298185

DIDO1
Death-inducer obliterator 1

1

9

Small-scale

0.479

High

1341491

RORB
Nuclear receptor ROR-beta

1

19

Small-scale

0.479

High

1353904

BASP1
Brain acid soluble protein 1

1

4

Small-scale

0.479

High

1353906

PSIP1
PC4 and SFRS1-interacting protein

1

4

Small-scale

0.479

High

1353910

CASZ1
Zinc finger protein castor homolog 1

1

5

Small-scale

0.479

High

1353912

KAT8
Histone acetyltransferase KAT8

1

4

Small-scale

0.479

High

1353915

ZNF22
Zinc finger protein 22

1

4

Small-scale

0.479

High

585428

FGF2
Fibroblast growth factor 2

1

0

Small-scale

0.458

High

868418

RL6
Large ribosomal subunit protein eL6

1

0

Small-scale

0.458

High

985986

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.458

High

1190835

ZNF48
Zinc finger protein 48

1

0

Small-scale

0.458

High

1222765

ZN638
Zinc finger protein 638

1

0

Small-scale

0.458

High

1353907

NXF1
Nuclear RNA export factor 1

1

0

Small-scale

0.458

High

1353908

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.458

High

1353911

SARNP
SAP domain-containing ribonucleoprotein

1

0

Small-scale

0.458

High

1353917

LANC2
LanC-like protein 2

1

0

Small-scale

0.458

High

109211

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

4

Small-scale

0.437

High

694430

RL3
Large ribosomal subunit protein uL3

1

1

Small-scale

0.437

High

983249

RS26
Small ribosomal subunit protein eS26

1

2

Small-scale

0.437

High

1197467

DDX17
Probable ATP-dependent RNA helicase DDX17

1

2

Small-scale

0.437

High

1209058

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

7

Small-scale

0.437

High

1229983

CDK13
Cyclin-dependent kinase 13

1

3

Small-scale

0.437

High

1295936

PDIP3
Polymerase delta-interacting protein 3

1

2

Small-scale

0.437

High

1297359

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

2

Small-scale

0.437

High

1353902

SFPQ
Splicing factor, proline- and glutamine-rich

1

5

Small-scale

0.437

High

1353916

RL38
Large ribosomal subunit protein eL38

1

1

Small-scale

0.437

High

619304

RL13A
Large ribosomal subunit protein uL13

1

0

Small-scale

0.249

Low

973117

RS29
Small ribosomal subunit protein uS14

1

0

Small-scale

0.249

Low

986314

RL8
Large ribosomal subunit protein uL2

1

0

Small-scale

0.249

Low

1353901

Z385A
Zinc finger protein 385A

1

0

Small-scale

0.249

Low

1353909

RS21
Small ribosomal subunit protein eS21

1

0

Small-scale

0.249

Low

1353913

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

Small-scale

0.249

Low

1353914

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025