Protein: LHX1
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)

Gene: LHX1
Organism: Homo sapiens
Interactions: 97
UniProt ID: P48742

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001655 - urogenital system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

877527

LDB1
LIM domain-binding protein 1

3

20

High-throughput

0.858

High

877521

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

18

High-throughput

0.700

High

877555

SSBP4
Single-stranded DNA-binding protein 4

4

20

High-throughput

0.699

High

877557

SSBP3
Single-stranded DNA-binding protein 3

4

20

High-throughput

0.699

High

877543

ISL2
Insulin gene enhancer protein ISL-2

1

17

High-throughput

0.691

High

733239

OTX2
Homeobox protein OTX2

1

19

Small-scale

0.647

High

877572

LHX3
LIM/homeobox protein Lhx3

1

18

Small-scale

0.647

High

877509

SATB1
DNA-binding protein SATB1

1

7

High-throughput

0.618

High

877515

MEF2D
Myocyte-specific enhancer factor 2D

1

3

High-throughput

0.618

High

877529

ZFHX4
Zinc finger homeobox protein 4

1

12

High-throughput

0.618

High

877531

MGAP
MAX gene-associated protein

1

8

High-throughput

0.618

High

877548

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

14

High-throughput

0.618

High

877564

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

11

High-throughput

0.618

High

877573

TRPS1
Zinc finger transcription factor Trps1

1

17

High-throughput

0.618

High

877575

SATB2
DNA-binding protein SATB2

1

7

High-throughput

0.618

High

877556

SCNM1
Sodium channel modifier 1

2

1

High-throughput

0.606

High

877519

CTSRT
Cation channel sperm-associated targeting subunit tau

2

1

High-throughput

0.553

High

877577

FOXA2
Hepatocyte nuclear factor 3-beta

1

4

Small-scale

0.501

High

550172

PABP1
Polyadenylate-binding protein 1

1

0

High-throughput

0.493

High

348419

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.479

High

877520

DGKK
Diacylglycerol kinase kappa

1

0

High-throughput

0.479

High

877578

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.479

High

138980

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

142892

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

154649

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

161433

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

180746

TIF1A
Transcription intermediary factor 1-alpha

1

9

High-throughput

0.479

High

194527

KDM6A
Lysine-specific demethylase 6A

1

5

High-throughput

0.479

High

238433

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

344892

WIZ
Protein Wiz

1

7

High-throughput

0.479

High

586247

ZEP1
Zinc finger protein 40

1

16

High-throughput

0.479

High

877503

CTCF
Transcriptional repressor CTCF

1

3

High-throughput

0.479

High

877505

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

12

High-throughput

0.479

High

877506

BLM
RecQ-like DNA helicase BLM

1

2

High-throughput

0.479

High

877507

SSBP2
Single-stranded DNA-binding protein 2

1

20

High-throughput

0.479

High

877510

TLE1
Transducin-like enhancer protein 1

1

11

High-throughput

0.479

High

877511

PWP1
Periodic tryptophan protein 1 homolog

1

3

High-throughput

0.479

High

877512

SMC1A
Structural maintenance of chromosomes protein 1A

1

4

High-throughput

0.479

High

877513

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.479

High

877516

OZF
Zinc finger protein OZF

1

3

High-throughput

0.479

High

877517

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

High-throughput

0.479

High

877518

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

8

High-throughput

0.479

High

877522

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

877524

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

12

High-throughput

0.479

High

877525

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.479

High

877526

POGZ
Pogo transposable element with ZNF domain

1

7

High-throughput

0.479

High

877528

PB1
Protein polybromo-1

1

16

High-throughput

0.479

High

877530

FOXP4
Forkhead box protein P4

1

15

High-throughput

0.479

High

877533

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

877534

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

877535

KDM2B
Lysine-specific demethylase 2B

1

5

High-throughput

0.479

High

877536

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

877537

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

8

High-throughput

0.479

High

877538

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

877539

KAT2B
Histone acetyltransferase KAT2B

1

12

High-throughput

0.479

High

877540

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

17

High-throughput

0.479

High

877541

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

5

High-throughput

0.479

High

877542

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

High-throughput

0.479

High

877544

ZBT10
Zinc finger and BTB domain-containing protein 10

1

9

High-throughput

0.479

High

877545

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

12

High-throughput

0.479

High

877547

Z512B
Zinc finger protein 512B

1

12

High-throughput

0.479

High

877549

ZN512
Zinc finger protein 512

1

8

High-throughput

0.479

High

877550

ARI3A
AT-rich interactive domain-containing protein 3A

1

20

High-throughput

0.479

High

877551

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

8

High-throughput

0.479

High

877553

PYGO2
Pygopus homolog 2

1

10

High-throughput

0.479

High

877559

GTPB4
GTP-binding protein 4

1

4

High-throughput

0.479

High

877560

REXO4
RNA exonuclease 4

1

1

High-throughput

0.479

High

877562

ZN644
Zinc finger protein 644

1

7

High-throughput

0.479

High

877563

DDX31
ATP-dependent DNA helicase DDX31

1

1

High-throughput

0.479

High

877565

BRD7
Bromodomain-containing protein 7

1

8

High-throughput

0.479

High

877566

TF7L2
Transcription factor 7-like 2

1

18

High-throughput

0.479

High

877570

DDX56
Probable ATP-dependent RNA helicase DDX56

1

5

High-throughput

0.479

High

877571

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

7

High-throughput

0.479

High

877576

SMC3
Structural maintenance of chromosomes protein 3

1

4

High-throughput

0.479

High

877582

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

877583

LAS1L
Ribosomal biogenesis protein LAS1L

1

1

High-throughput

0.479

High

877584

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

7

High-throughput

0.479

High

877585

NCOR2
Nuclear receptor corepressor 2

1

12

High-throughput

0.479

High

877523

NEPRO
Nucleolus and neural progenitor protein

1

0

High-throughput

0.458

High

877532

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.458

High

877569

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.458

High

877504

TMEDA
Transmembrane emp24 domain-containing protein 10

1

4

High-throughput

0.457

High

877554

TMED9
Transmembrane emp24 domain-containing protein 9

1

3

High-throughput

0.457

High

877579

TMED5
Transmembrane emp24 domain-containing protein 5

1

4

High-throughput

0.457

High

140807

NOP56
Nucleolar protein 56

1

1

High-throughput

0.437

High

345514

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.437

High

877508

RT15
Small ribosomal subunit protein uS15m

1

1

High-throughput

0.437

High

877546

DDX27
Probable ATP-dependent RNA helicase DDX27

1

2

High-throughput

0.437

High

877552

CHOLN
Protein cholesin

1

3

High-throughput

0.437

High

877558

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

1

High-throughput

0.437

High

877561

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

877568

RBM28
RNA-binding protein 28

1

3

High-throughput

0.437

High

877574

RL26L
Ribosomal protein uL24-like

1

2

High-throughput

0.437

High

877580

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.437

High

877581

NOP16
Nucleolar protein 16

1

1

High-throughput

0.437

High

877514

BMS1
Ribosome biogenesis protein BMS1 homolog

1

0

High-throughput

0.249

Low

877567

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025