HitPredict

Interactor 1: RS2 (P15880)
Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (40S ribosomal protein S4) (Protein LLRep3)
Gene: RPS2

Interactor 2: IF4A3 (P38919)
Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Eukaryotic translation initiation factor 4A isoform 3) (Nuclear matrix protein 265) (NMP 265) (hNMP 265) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]
Gene: EIF4A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23084401
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 411
+	Sc
		631886 RS2_YEAST (55-279): 1.72e-102: 301: 59.56		DHH1_YEAST (39-408): 1.26e-169: 486: 40.54
+	Sc
		485660 RS2_YEAST (55-279): 1.72e-102: 301: 59.56		IF4A_YEAST (22-411): 6.11e-163: 465: 62.31
+	Sc
		624027 RS2_YEAST (55-279): 1.72e-102: 301: 59.56		DBP2_YEAST (4-409): 1.37e-135: 400: 32.37
+	Sc
		624208 RS2_YEAST (55-279): 1.72e-102: 301: 59.56		DBP1_YEAST (18-410): 1.29e-130: 390: 32.77
+	Sc
		415897 RS2_YEAST (55-279): 1.72e-102: 301: 59.56		DED1_YEAST (6-411): 3.66e-130: 388: 32.00
+	Hs
		550613 RS2_HUMAN (1-293): 1.3e-137: 392: 100.00		DDX6_HUMAN (35-407): 1.15e-88: 278: 37.83
+	Sc
		415936 RT05_YEAST (95-251): 3.11e-41: 146: 27.85		DED1_YEAST (6-411): 3.66e-130: 388: 32.00