HitPredict

Interactor 1: ITF2 (P15884)
Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: TCF4

Interactor 2: HM20A (Q9NP66)
High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)
Gene: HMG20A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 347
+	Hs
		551234 ITF2_HUMAN (1-667): 0: 908: 100.00		SMCE1_HUMAN (109-299): 6.51e-34: 130: 20.00
+	Hs
		449521 ITF2_HUMAN (1-667): 0: 908: 100.00		HMGB1_HUMAN (97-265): 2.13e-15: 76.2: 19.65
+	Hs
		818384 HTF4_HUMAN (3-667): 0: 783: 61.71		SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42
+	Mm
		981836 HTF4_MOUSE (3-667): 0: 771: 59.22		SOX8_MOUSE (11-206): 8.45e-30: 120: 12.76
+	Hs
		551482 TFE2_HUMAN (1-667): 0: 733: 49.71		SOX2_HUMAN (68-269): 3.13e-31: 121: 15.42
+	Mm
		222662 TFE2_MOUSE (1-667): 0: 702: 47.69		SMCE1_MOUSE (109-299): 1.02e-32: 127: 20.00