Protein: RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)

Gene: RAD18
Organism: Saccharomyces cerevisiae S288C
Interactions: 30
UniProt ID: P10862

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0006301 - postreplication repair
GO:0006513 - protein monoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438516

UBC2
Ubiquitin-conjugating enzyme E2 2

21

20

Small-scale

0.991

High

533464

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

5

16

Small-scale

0.919

High

533479

UBC9
SUMO-conjugating enzyme UBC9

3

20

Small-scale

0.863

High

533480

UBC13
Ubiquitin-conjugating enzyme E2 13

2

20

Small-scale

0.802

High

509356

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

19

Small-scale

0.778

High

533467

PCNA
Proliferating cell nuclear antigen

13

4

Small-scale

0.760

High

533473

RAD5
DNA repair protein RAD5

4

9

Small-scale

0.696

High

533466

SRS2
ATP-dependent DNA helicase SRS2

2

1

Small-scale

0.584

High

533469

RFA1
Replication factor A protein 1

1

3

Small-scale

0.573

High

533470

RFA2
Replication factor A protein 2

1

2

Small-scale

0.527

High

533485

SMT3
Ubiquitin-like protein SMT3

1

4

Small-scale

0.527

High

533475

LSM2
LSM complex subunit LSM2

1

3

High-throughput

0.508

High

533481

LSM3
LSM complex subunit LSM3

1

1

High-throughput

0.508

High

533478

RAD17
DNA damage checkpoint control protein RAD17

1

0

Small-scale

0.486

High

533483

POLH
DNA polymerase eta

1

4

Small-scale

0.481

High

408274

GAL1
Galactokinase

1

0

High-throughput

0.479

High

533472

MRE11
Double-strand break repair protein MRE11

1

1

Small-scale

0.479

High

533468

PUR6
Phosphoribosylaminoimidazole carboxylase

1

5

High-throughput

0.464

High

533482

MUB1
MYND-type zinc finger protein MUB1

1

0

High-throughput

0.458

High

533474

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.457

High

533484

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

10

High-throughput

0.457

High

522848

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

525740

HSP72
Heat shock protein SSA2

1

20

High-throughput

0.445

High

533465

SSB1
Ribosome-associated molecular chaperone SSB1

1

19

High-throughput

0.445

High

533471

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

533487

AP2M
AP-2 complex subunit mu

1

1

Small-scale

0.439

High

533486

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.251

Low

533476

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

533477

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025