HitPredict

Interactor 1: RAG1 (P15919)
V(D)J recombination-activating protein 1 (RAG-1) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: RAG1 (P15919)
V(D)J recombination-activating protein 1 (RAG-1) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 14671314, 19396172, 21149691
Identification Methods enzymatic study, molecular sieving, light scattering, x-ray crystallography, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RAG1~RAG1, RAG1_imp_bd~zf-C3HC4, RAG1_imp_bd~zf-RAG1
Common GO terms GO:0002250 - adaptive immune response
GO:0002331 - pre-B cell allelic exclusion
GO:0004519 - endonuclease activity
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
and 24 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024