HitPredict

Interactor 1: RAG1 (P15919)
V(D)J recombination-activating protein 1 (RAG-1) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: RAG2 (P21784)
V(D)J recombination-activating protein 2 (RAG-2)
Gene: RAG2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

The method score is based on:

Property	Details
Experiments	21149691, 19396172, 25707801, 22157821
Identification Methods	cross-linking study, molecular sieving, pull down, x-ray crystallography
Interaction Type	direct interaction, association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RAG1~RAG2
Common GO terms	GO:0002331 - pre-B cell allelic exclusion GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006310 - DNA recombination GO:0006325 - chromatin organization and 7 others more... GO:0008270 - zinc ion binding GO:0030183 - B cell differentiation GO:0033077 - T cell differentiation in thymus GO:0033151 - V(D)J recombination GO:0043565 - sequence-specific DNA binding GO:0061630 - ubiquitin protein ligase activity GO:0097519 - DNA recombinase complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	1040
Mm

1	527

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024