Protein: APLP1
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]

Gene: APLP1
Organism: Homo sapiens
Interactions: 66
UniProt ID: P51693

Gene Ontology (top 5):
GO:0005604 - basement membrane
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006417 - regulation of translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

907324

APBB2
Amyloid beta precursor protein binding family B member 2

4

13

High-throughput

0.892

High

127032

APBB1
Amyloid beta precursor protein binding family B member 1

3

13

Small-scale

0.866

High

907299

APLP1
Amyloid beta precursor like protein 1

2

10

Small-scale

0.812

High

342398

APBB3
Amyloid-beta A4 precursor protein-binding family B member 3

3

13

Small-scale

0.774

High

286350

DAB1
Disabled homolog 1

1

16

Small-scale

0.740

High

421754

A4
Amyloid-beta precursor protein

1

15

Small-scale

0.681

High

907309

APLP2
Amyloid beta precursor like protein 2

1

12

Small-scale

0.681

High

317116

CNTN5
Contactin-5

1

8

Small-scale

0.647

High

907306

DAB2
Disabled homolog 2

1

15

Small-scale

0.647

High

907321

CNTN4
Contactin-4

1

8

Small-scale

0.647

High

907332

CNTN3
Contactin-3

1

8

Small-scale

0.647

High

410724

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

12

High-throughput

0.637

High

907317

T22D1
TSC22 domain family protein 1

2

4

High-throughput

0.620

High

907329

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

2

2

High-throughput

0.613

High

600272

ZNF24
Zinc finger protein 24

1

14

High-throughput

0.582

High

405421

KITH
Thymidine kinase, cytosolic

2

1

High-throughput

0.566

High

846046

GLP1R
Glucagon-like peptide 1 receptor

1

3

Small-scale

0.552

High

223959

TCF21
Transcription factor 21

1

1

High-throughput

0.541

High

907311

STX5
Syntaxin-5

1

9

High-throughput

0.541

High

907322

PHF10
PHD finger protein 10

1

3

High-throughput

0.541

High

907327

TOE1
Target of EGR1 protein 1

1

2

High-throughput

0.541

High

907328

MPH6
M-phase phosphoprotein 6

1

2

High-throughput

0.541

High

907336

PCDA4
Protocadherin alpha-4

1

4

High-throughput

0.541

High

882415

ARRB1
Beta-arrestin-1

1

1

High-throughput

0.536

High

380413

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

0

High-throughput

0.518

High

474560

VIME
Vimentin

1

7

High-throughput

0.508

High

549100

CDK4
Cyclin-dependent kinase 4

1

5

High-throughput

0.508

High

616276

RCC1
Regulator of chromosome condensation

1

1

High-throughput

0.508

High

627940

ANXA7
Annexin A7

1

3

High-throughput

0.508

High

791196

SYUA
Alpha-synuclein

1

3

High-throughput

0.508

High

807992

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.508

High

907301

RAP1B
Ras-related protein Rap-1b

1

13

High-throughput

0.508

High

907313

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

High-throughput

0.508

High

907326

MED12
Mediator of RNA polymerase II transcription subunit 12

1

5

Small-scale

0.501

High

361787

PNPH
Purine nucleoside phosphorylase

1

1

High-throughput

0.494

High

627621

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

2

High-throughput

0.494

High

639590

SAT1
Diamine acetyltransferase 1

1

1

High-throughput

0.494

High

842944

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

6

High-throughput

0.494

High

907307

GSTM4
Glutathione S-transferase Mu 4

1

3

High-throughput

0.494

High

907314

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.494

High

907304

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

907318

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

907305

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.481

High

907323

ING5
Inhibitor of growth protein 5

1

3

High-throughput

0.481

High

907325

KAT5
Histone acetyltransferase KAT5

1

3

Small-scale

0.481

High

370607

FOS
Protein c-Fos

1

9

High-throughput

0.479

High

774221

BASI
Basigin

1

6

High-throughput

0.479

High

907308

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

9

Small-scale

0.479

High

907310

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

9

Small-scale

0.479

High

907312

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

9

Small-scale

0.479

High

907330

SPON1
Spondin-1

1

6

Small-scale

0.479

High

907333

VPS29
Vacuolar protein sorting-associated protein 29

1

1

High-throughput

0.470

High

907316

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.460

High

907319

RBM48
RNA-binding protein 48

1

0

High-throughput

0.460

High

907320

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

907335

PILRA
Paired immunoglobulin-like type 2 receptor alpha

1

0

Small-scale

0.458

High

254893

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.445

High

907315

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

907331

MED4
Mediator of RNA polymerase II transcription subunit 4

1

2

Small-scale

0.445

High

105608

APRIO
Alternative prion protein

1

1

Small-scale

0.439

High

248388

GDF9
Growth/differentiation factor 9

1

5

High-throughput

0.439

High

907300

HAP1
Huntingtin-associated protein 1

1

2

High-throughput

0.439

High

907303

TYB4
Thymosin beta-4

1

1

High-throughput

0.417

High

907302

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.282

High

907334

CRCT1
Cysteine-rich C-terminal protein 1

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025