HitPredict

Interactor 1: ADT3 (P12236)
ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene: SLC25A6

Interactor 2: SMUF2 (Q9HAU4)
E3 ubiquitin-protein ligase SMURF2 (hSMURF2) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF2) (SMAD ubiquitination regulatory factor 2) (SMAD-specific E3 ubiquitin-protein ligase 2)
Gene: SMURF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23973329
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 748
+	Hs
		425039 ADT2_HUMAN (1-297): 3.67e-112: 327: 92.26		SMUF2_HUMAN (1-748): 0: 837: 100.00
+	Hs
		425044 ADT2_HUMAN (1-297): 3.67e-112: 327: 92.26		SMUF1_HUMAN (1-748): 0: 753: 70.31
+	Hs
		552295 ADT3_HUMAN (1-298): 2.42e-114: 333: 100.00		HUWE1_HUMAN (114-747): 0: 591: 31.46
+	Hs
		424946 ADT2_HUMAN (1-297): 3.67e-112: 327: 92.26		HUWE1_HUMAN (114-747): 0: 591: 31.46
+	Hs
		1280581 S2513_HUMAN (3-271): 2.44e-43: 158: 18.96		HUWE1_HUMAN (114-747): 0: 591: 31.46
+	Sc
		613626 ADT2_YEAST (8-206): 2.95e-38: 139: 24.62		TOM1_YEAST (325-747): 1.65e-164: 528: 40.47
+	Hs
		424996 ADT2_HUMAN (1-297): 3.67e-112: 327: 92.26		ITCH_HUMAN (1-426): 1.04e-26: 118: 17.13
+	Hs
		131659 ADT2_HUMAN (1-297): 3.67e-112: 327: 92.26		WWP2_HUMAN (1-416): 3.08e-25: 114: 15.94
+	Hs
		552425 ADT3_HUMAN (1-298): 2.42e-114: 333: 100.00		HECW2_HUMAN (19-281): 1.72e-15: 83.3: 13.46