HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 3969
+	Hs
		554048 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2B_HUMAN (3163-3969): 3.56e-127: 454: 36.71
+	Hs
		165620 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SET1A_HUMAN (3695-3969): 8.18e-56: 218: 34.58
+	Hs
		1026531 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		SETD2_HUMAN (3398-3968): 1.14e-75: 285: 16.61
+	Hs
		553224 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2C_HUMAN (384-1407): 6.81e-11: 71.4: 10.23
+	Hs
		553508 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MINT_HUMAN (418-1102): 7.18e-09: 64.7: 11.18
+	Hs
		152585 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2D_HUMAN (11-1393): 8.17e-09: 64.4: 10.47