HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36688959, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding GO:2000001 - regulation of DNA damage checkpoint
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 759
+	Hs
		552676 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		552674 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		552672 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		552673 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL2_HUMAN (51-759): 0: 710: 27.00
+	Hs
		553360 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CUL5_HUMAN (59-759): 0: 589: 24.94