HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: HLTF (Q14527)
Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3)
Gene: HLTF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26186194, 24981860, 24332808
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 1009
+	Hs
		552270 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA4_HUMAN (94-918): 4.65e-157: 507: 15.16
+	Hs
		552269 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA2_HUMAN (94-909): 4.19e-152: 492: 14.90
+	Hs
		553828 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		HELLS_HUMAN (241-1009): 3.24e-156: 484: 18.88
+	Hs
		553704 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMRCD_HUMAN (193-1009): 1.61e-152: 480: 18.47
+	Hs
		229295 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMCA5_HUMAN (288-928): 7.49e-149: 471: 16.11
+	Hs
		554141 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		ARIP4_HUMAN (176-1006): 4.18e-144: 468: 15.88
+	Hs
		554060 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		TTF2_HUMAN (397-1009): 9.33e-138: 445: 26.52
+	Hs
		163559 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		BTAF1_HUMAN (377-1007): 2.39e-115: 393: 19.76