Protein: CIP2A
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)

Gene: CIP2A
Organism: Homo sapiens
Interactions: 198
UniProt ID: Q8TCG1

Gene Ontology (top 5):
GO:0004864 - protein phosphatase inhibitor activity
GO:0005694 - chromosome
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1349668

CIP2A
Protein CIP2A

3

19

Small-scale

0.875

High

262272

SCN2B
Sodium channel regulatory subunit beta-2

4

5

High-throughput

0.691

High

166359

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

4

1

High-throughput

0.678

High

906122

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

1

High-throughput

0.667

High

1349680

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

5

High-throughput

0.667

High

1349703

PD1L1
Programmed cell death 1 ligand 1

3

9

High-throughput

0.667

High

1349710

CAH14
Carbonic anhydrase 14

3

1

High-throughput

0.667

High

835335

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

2

High-throughput

0.662

High

372650

MYC
Myc proto-oncogene protein

2

3

Small-scale

0.636

High

466940

ACM4
Muscarinic acetylcholine receptor M4

2

1

High-throughput

0.628

High

665322

EDNRB
Endothelin receptor type B

2

5

High-throughput

0.628

High

699567

IL1R2
Interleukin-1 receptor type 2

2

1

High-throughput

0.628

High

879809

NPY2R
Neuropeptide Y receptor type 2

2

2

High-throughput

0.628

High

1232099

VASN
Vasorin

2

3

High-throughput

0.628

High

1245254

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

2

3

High-throughput

0.628

High

1349696

LRRC4
Leucine-rich repeat-containing protein 4

2

6

High-throughput

0.628

High

845460

PE2R3
Prostaglandin E2 receptor EP3 subtype

2

2

High-throughput

0.611

High

1326196

PNKD
Probable thioesterase PNKD

2

4

High-throughput

0.611

High

1186219

CEA21
Cell adhesion molecule CEACAM21

3

2

High-throughput

0.609

High

1291637

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

1

High-throughput

0.609

High

702815

5HT2C
5-hydroxytryptamine receptor 2C

2

0

High-throughput

0.602

High

1029619

CD83
CD83 antigen

2

0

High-throughput

0.602

High

1349709

FZD10
Frizzled-10

2

0

High-throughput

0.602

High

638478

FPR1
fMet-Leu-Phe receptor

2

6

High-throughput

0.601

High

683292

TNR5
Tumor necrosis factor receptor superfamily member 5

2

1

High-throughput

0.601

High

1022919

EFNB1
Ephrin-B1

2

5

High-throughput

0.601

High

1101601

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

7

High-throughput

0.601

High

1349716

NPTN
Neuroplastin

2

2

High-throughput

0.601

High

717913

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

0

Small-scale

0.588

High

363596

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.584

High

799320

BRCA1
Breast cancer type 1 susceptibility protein

2

7

High-throughput

0.584

High

1103135

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

1

Small-scale

0.573

High

1349711

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

Small-scale

0.561

High

1349670

TOPB1
DNA topoisomerase 2-binding protein 1

2

0

Small-scale

0.559

High

1349675

LRC59
Leucine-rich repeat-containing protein 59

1

5

Small-scale

0.552

High

133285

P2Y10
Putative P2Y purinoceptor 10

1

9

High-throughput

0.536

High

182681

GP182
G-protein coupled receptor 182

1

8

High-throughput

0.536

High

209077

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.536

High

210413

MTLR
Motilin receptor

1

4

High-throughput

0.536

High

388255

GLPA
Glycophorin-A

1

1

High-throughput

0.536

High

486593

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.536

High

540580

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.536

High

564106

CFTR
Cystic fibrosis transmembrane conductance regulator

1

11

High-throughput

0.536

High

640428

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

5

High-throughput

0.536

High

690317

STOM
Stomatin

1

1

High-throughput

0.536

High

719819

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.536

High

867289

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

867994

GLR
Glucagon receptor

1

3

High-throughput

0.536

High

901416

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.536

High

914305

EFNA4
Ephrin-A4

1

5

High-throughput

0.536

High

914544

EFNA5
Ephrin-A5

1

5

High-throughput

0.536

High

936092

PAR2
Proteinase-activated receptor 2

1

7

High-throughput

0.536

High

956948

CXCR4
C-X-C chemokine receptor type 4

1

5

High-throughput

0.536

High

976438

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.536

High

1132564

FXYD3
FXYD domain-containing ion transport regulator 3

1

1

High-throughput

0.536

High

1142108

P2RY6
P2Y purinoceptor 6

1

9

High-throughput

0.536

High

1249820

BTNL9
Butyrophilin-like protein 9

1

5

High-throughput

0.536

High

1291845

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

8

High-throughput

0.536

High

1349684

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

2

High-throughput

0.536

High

1349688

FXYD6
FXYD domain-containing ion transport regulator 6

1

1

High-throughput

0.536

High

1349691

TSN10
Tetraspanin-10

1

7

High-throughput

0.536

High

642982

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.515

High

253869

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.513

High

303688

JTB
Protein JTB

1

0

High-throughput

0.513

High

587355

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

1

0

High-throughput

0.513

High

1349681

OPALI
Opalin

1

0

High-throughput

0.513

High

1349686

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.513

High

1349687

SEM4C
Semaphorin-4C

1

0

High-throughput

0.513

High

1349704

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1349713

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

71232

HIDE1
Protein HIDE1

1

1

High-throughput

0.489

High

1293872

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

4

High-throughput

0.489

High

1349689

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

164024

NDC80
Kinetochore protein NDC80 homolog

1

15

Small-scale

0.481

High

250724

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

Small-scale

0.481

High

324183

CE152
Centrosomal protein of 152 kDa

1

15

Small-scale

0.481

High

325944

UBR5
E3 ubiquitin-protein ligase UBR5

1

5

Small-scale

0.481

High

443454

CDK1
Cyclin-dependent kinase 1

1

8

Small-scale

0.481

High

699810

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.481

High

908842

NEK2
Serine/threonine-protein kinase Nek2

1

10

Small-scale

0.481

High

913962

RBM5
RNA-binding protein 5

1

1

Small-scale

0.481

High

1041837

CENPC
Centromere protein C

1

1

Small-scale

0.481

High

1105638

GOGA4
Golgin subfamily A member 4

1

16

Small-scale

0.481

High

1313283

SMC5
Structural maintenance of chromosomes protein 5

1

14

Small-scale

0.481

High

1349683

RING2
E3 ubiquitin-protein ligase RING2

1

7

Small-scale

0.481

High

1349708

WWC3
Protein WWC3

1

11

Small-scale

0.481

High

165741

PPE2
Serine/threonine-protein phosphatase with EF-hands 2

1

6

High-throughput

0.479

High

173114

XPO1
Exportin-1

1

2

High-throughput

0.479

High

176272

SYNJ2
Synaptojanin-2

1

1

High-throughput

0.479

High

177026

CE290
Centrosomal protein of 290 kDa

1

17

High-throughput

0.479

High

247389

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

3

High-throughput

0.479

High

290088

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

412298

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

457575

TBB5
Tubulin beta chain

1

2

High-throughput

0.479

High

487556

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

488520

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

3

Small-scale

0.479

High

613410

VINC
Vinculin

1

8

High-throughput

0.479

High

696008

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

705716

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

2

High-throughput

0.479

High

727895

DNJA1
DnaJ homolog subfamily A member 1

1

1

High-throughput

0.479

High

731489

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

791560

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

891253

GSK3A
Glycogen synthase kinase-3 alpha

1

10

High-throughput

0.479

High

891685

GSK3B
Glycogen synthase kinase-3 beta

1

10

High-throughput

0.479

High

934893

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

942769

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

10

High-throughput

0.479

High

958473

ACTZ
Alpha-centractin

1

11

High-throughput

0.479

High

959217

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

1051024

FAK1
Focal adhesion kinase 1

1

9

High-throughput

0.479

High

1109920

HDAC1
Histone deacetylase 1

1

9

High-throughput

0.479

High

1113783

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1135746

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.479

High

1164057

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

3

High-throughput

0.479

High

1178269

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1246890

RICTR
Rapamycin-insensitive companion of mTOR

1

2

High-throughput

0.479

High

1254759

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1256526

CE128
Centrosomal protein of 128 kDa

1

16

High-throughput

0.479

High

1272853

TAOK1
Serine/threonine-protein kinase TAO1

1

18

High-throughput

0.479

High

1280353

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

1288685

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

11

High-throughput

0.479

High

1316507

UNC5B
Netrin receptor UNC5B

1

1

Small-scale

0.479

High

1322759

CNTRB
Centrobin

1

17

High-throughput

0.479

High

1339623

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1349423

POC1B
POC1 centriolar protein homolog B

1

6

High-throughput

0.479

High

1349669

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1349671

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1349682

FMNL2
Formin-like protein 2

1

3

High-throughput

0.479

High

1349692

GAN
Gigaxonin

1

5

High-throughput

0.479

High

1349693

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.479

High

1349694

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1349695

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1349705

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1349712

DUS12
Dual specificity protein phosphatase 12

1

2

High-throughput

0.479

High

1349717

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

2

High-throughput

0.479

High

1311694

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

12

High-throughput

0.470

High

680964

PSA1
Proteasome subunit alpha type-1

1

0

Small-scale

0.460

High

681459

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.460

High

1169020

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

Small-scale

0.460

High

245346

CE104
Centrosomal protein of 104 kDa

1

0

High-throughput

0.458

High

294070

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

326591

MFN2
Mitofusin-2

1

0

High-throughput

0.458

High

552649

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

556231

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

582594

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

1004873

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1095148

RED
Protein Red

1

0

Small-scale

0.458

High

1100913

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1107951

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1204378

SGO1
Shugoshin 1

1

0

Small-scale

0.458

High

1249042

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1252903

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1293620

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1332871

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1349673

SYMPK
Symplekin

1

0

High-throughput

0.458

High

1349677

ARMC5
Armadillo repeat-containing protein 5

1

0

High-throughput

0.458

High

1349679

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1349697

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

0

High-throughput

0.458

High

171524

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.445

High

484186

PGFRB
Platelet-derived growth factor receptor beta

1

3

High-throughput

0.445

High

610023

VGFR1
Vascular endothelial growth factor receptor 1

1

2

Small-scale

0.445

High

754073

CD80
T-lymphocyte activation antigen CD80

1

7

High-throughput

0.445

High

1209423

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1227112

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.445

High

1243634

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.445

High

1349672

LPAR1
Lysophosphatidic acid receptor 1

1

1

High-throughput

0.445

High

1349700

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

1

High-throughput

0.445

High

1349714

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.445

High

1349715

S27A5
Long-chain fatty acid transport protein 5

1

3

High-throughput

0.445

High

937419

LAMB2
Laminin subunit beta-2

1

1

Small-scale

0.439

High

106329

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

246796

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.437

High

589225

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

768707

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1241912

FBX42
F-box only protein 42

1

9

High-throughput

0.437

High

1276519

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1349674

MFRN2
Mitoferrin-2

1

1

High-throughput

0.437

High

1349676

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

1349701

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

5

High-throughput

0.437

High

1349707

RCOR1
REST corepressor 1

1

1

High-throughput

0.437

High

1289140

OSTA
Organic solute transporter subunit alpha

1

0

High-throughput

0.426

High

50635

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.407

High

1313967

S35F3
Solute carrier family 35 member F3

1

1

High-throughput

0.407

High

1349702

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.407

High

1349718

X6RFA8
Solute carrier family 25 member 28

1

1

High-throughput

0.407

High

1330718

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1349706

CC018
Uncharacterized protein C3orf18

2

0

High-throughput

0.313

High

141782

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

0

High-throughput

0.279

Low

1272638

ENOF1
Mitochondrial enolase superfamily member 1

1

0

High-throughput

0.279

Low

1349690

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1349698

Q9HCK3
KIAA1569 protein

1

0

Small-scale

0.251

Low

880621

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1105354

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.249

Low

1312398

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.249

Low

1349685

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.249

Low

1349699

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

1234020

S35E4
Solute carrier family 35 member E4

1

0

High-throughput

0.232

Low

1349678

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025