Interactor 1: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2
Interactor 2: RGMA (Q96B86)
Repulsive guidance molecule A (RGM domain family member A)
Gene: RGMA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25938661 |
| Identification Methods | surface plasmon resonance, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RGM_C~TGF_beta, RGM_N~TGF_beta |
| Common GO terms | GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0030509 - BMP signaling pathway GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
