Interactor 1: HMDH1 (P12683)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (HMG-CoA reductase 1) (EC 1.1.1.34)
Gene: HMG1
Interactor 2: HMDH1 (P12683)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (HMG-CoA reductase 1) (EC 1.1.1.34)
Gene: HMG1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 1.00 | 0.743 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16093310, unassigned1933 |
| Identification Methods | protein complementation assay, dihydrofolate reductase reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HMG-CoA_red~HMG-CoA_red |
| Common GO terms | GO:0004420 - hydroxymethylglutaryl-CoA reductase (NADPH) activity GO:0005635 - nuclear envelope GO:0005778 - peroxisomal membrane GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane and 4 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
