Interactor 1: ANPRA (P16066)
Atrial natriuretic peptide receptor 1 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type A) (ANP-A) (ANPR-A) (NPR-A) (Guanylate cyclase A) (GC-A)
Gene: NPR1
Interactor 2: ANFC (P23582)
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
Gene: NPPC
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 1660465 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ANF_receptor~ANP |
| Common GO terms | GO:0006182 - cGMP biosynthetic process GO:0007168 - receptor guanylyl cyclase signaling pathway GO:0010753 - positive regulation of cGMP-mediated signaling GO:0019934 - cGMP-mediated signaling GO:0097746 - blood vessel diameter maintenance |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
