HitPredict

Interactor 1: CD44 (P16070)
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
Gene: CD44

Interactor 2: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.690

Property	Details
Experiments	19351837, 28205554, 17891137, 24912773
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, pull down, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 595
+	Hs
		546916 CD44_HUMAN (1-742): 0: 610: 100.00		EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20
+	Hs
		555079 CD44_HUMAN (1-742): 0: 610: 100.00		MOES_HUMAN (19-595): 5.97e-146: 435: 44.44
+	Mm
		548142 CD44_MOUSE (1-742): 0: 540: 65.90		RADI_MOUSE (19-595): 2.14e-149: 444: 45.64
+	Hs
		297816 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		RADI_HUMAN (19-595): 5.41e-151: 448: 45.47
+	Hs
		297842 K0754_HUMAN (216-656): 5.15e-32: 136: 10.08		E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46