Protein: NEK9
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8)

Gene: NEK9
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q8TD19

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1254381

NEK6
Serine/threonine-protein kinase Nek6

8

19

Small-scale

0.974

High

1254355

NEK7
Serine/threonine-protein kinase Nek7

5

18

Small-scale

0.934

High

331050

PAK4
Serine/threonine-protein kinase PAK 4

2

16

High-throughput

0.811

High

154218

CHK1
Serine/threonine-protein kinase Chk1

2

12

Small-scale

0.789

High

928405

DYL1
Dynein light chain 1, cytoplasmic

7

5

High-throughput

0.751

High

919180

RAN
GTP-binding nuclear protein Ran

1

8

Small-scale

0.724

High

861856

PLK1
Serine/threonine-protein kinase PLK1

1

16

Small-scale

0.700

High

1254363

DYL2
Dynein light chain 2, cytoplasmic

4

5

High-throughput

0.694

High

243517

DNJA2
DnaJ homolog subfamily A member 2

1

6

High-throughput

0.691

High

1073079

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.691

High

438382

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.665

High

1254357

TITIN
Titin

1

0

High-throughput

0.663

High

306243

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

19

Small-scale

0.649

High

476090

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

13

High-throughput

0.647

High

1197672

NEK8
Serine/threonine-protein kinase Nek8

1

19

Small-scale

0.647

High

891234

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

19

High-throughput

0.646

High

1254375

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

3

19

Small-scale

0.641

High

1254389

MAFF
Transcription factor MafF

3

0

High-throughput

0.638

High

1254372

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

19

Small-scale

0.636

High

1254192

BICD2
Protein bicaudal D homolog 2

2

20

Small-scale

0.634

High

1168524

RN19B
E3 ubiquitin-protein ligase RNF19B

2

10

High-throughput

0.628

High

160674

AURKA
Aurora kinase A

1

17

High-throughput

0.618

High

228141

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

385213

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.618

High

432092

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

779781

CCNF
Cyclin-F

1

9

High-throughput

0.618

High

932274

ACTC
Actin, alpha cardiac muscle 1

1

9

High-throughput

0.618

High

1192132

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

15

High-throughput

0.618

High

347403

MYC
Myc proto-oncogene protein

2

12

High-throughput

0.611

High

1254371

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

2

7

High-throughput

0.611

High

1254380

EMAL4
Echinoderm microtubule-associated protein-like 4

2

9

Small-scale

0.611

High

996784

SSRP1
FACT complex subunit SSRP1

2

3

Small-scale

0.601

High

1254379

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

2

0

Small-scale

0.593

High

1254374

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

19

High-throughput

0.586

High

808791

YAP1
Transcriptional coactivator YAP1

2

18

Small-scale

0.584

High

1130360

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

15

High-throughput

0.575

High

1254354

NEK9
Serine/threonine-protein kinase Nek9

1

18

High-throughput

0.575

High

906035

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

14

High-throughput

0.571

High

1254376

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.553

High

127925

EMAL1
Echinoderm microtubule-associated protein-like 1

1

9

High-throughput

0.536

High

509065

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.536

High

1057325

SMC1A
Structural maintenance of chromosomes protein 1A

1

19

High-throughput

0.536

High

1218850

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1254359

FAN
Protein FAN

1

6

High-throughput

0.536

High

1254361

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.536

High

1254368

TBA1C
Tubulin alpha-1C chain

1

17

High-throughput

0.536

High

1254382

E41L5
Band 4.1-like protein 5

1

9

High-throughput

0.536

High

1254384

PRD11
PR domain-containing protein 11

1

2

High-throughput

0.536

High

1254369

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

19

High-throughput

0.527

High

559188

H15
Histone H1.5

1

2

High-throughput

0.515

High

324519

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.513

High

1128347

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1254370

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1254377

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

163037

XPO1
Exportin-1

1

17

High-throughput

0.479

High

215537

CF410
Cilia- and flagella-associated protein 410

1

6

High-throughput

0.479

High

232363

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

387164

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

487606

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

489168

H14
Histone H1.4

1

2

High-throughput

0.479

High

553257

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

651759

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

684225

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

684908

STIP1
Stress-induced-phosphoprotein 1

1

9

High-throughput

0.479

High

720982

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

908859

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.479

High

909842

1433E
14-3-3 protein epsilon

1

19

High-throughput

0.479

High

962882

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.479

High

998906

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1035912

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1038562

HDAC1
Histone deacetylase 1

1

9

High-throughput

0.479

High

1042110

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1043115

CUL4A
Cullin-4A

1

8

High-throughput

0.479

High

1064513

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1104134

EMAL3
Echinoderm microtubule-associated protein-like 3

1

11

High-throughput

0.479

High

1119003

AMOT
Angiomotin

1

19

High-throughput

0.479

High

1188597

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1200513

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1254356

NUDC2
NudC domain-containing protein 2

1

5

High-throughput

0.479

High

1254358

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

1254362

PF21A
PHD finger protein 21A

1

5

High-throughput

0.479

High

1254366

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1254373

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1254378

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1254387

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1254388

RCOR1
REST corepressor 1

1

4

High-throughput

0.479

High

1254360

ATOH1
Transcription factor ATOH1

1

0

Small-scale

0.458

High

1254383

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

409380

CASB
Beta-casein

1

2

Small-scale

0.457

High

1220071

KIBRA
Protein KIBRA

1

15

High-throughput

0.445

High

205729

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

786739

GRIA2
Glutamate receptor 2

1

2

High-throughput

0.437

High

1048876

BOP1
Ribosome biogenesis protein BOP1

1

3

High-throughput

0.437

High

1156275

RETST
All-trans-retinol 13,14-reductase

1

4

High-throughput

0.437

High

1160945

CTR9
RNA polymerase-associated protein CTR9 homolog

1

6

High-throughput

0.437

High

1254386

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

6

High-throughput

0.437

High

1022555

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

382488

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

2

High-throughput

0.407

High

1169879

PKHG7
Pleckstrin homology domain-containing family G member 7

1

12

High-throughput

0.407

High

1254364

NEUL4
Neuralized-like protein 4

1

1

High-throughput

0.407

High

535666

EDN3
Endothelin-3

1

0

High-throughput

0.279

Low

1102609

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1235179

CB073
Uncharacterized protein C2orf73

1

0

High-throughput

0.279

Low

1254365

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

1254367

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

967594

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.249

Low

1102461

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.249

Low

1254385

FAME
Factor associated with metabolism and energy

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024