HitPredict

Interactor 1: SPTN1 (P16086)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: GRIA4 (P19493)
Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (GluA4)
Gene: GRIA4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20131911
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2472 Rn			1 902
+	Hs
		786733 SPTN1_HUMAN (3-2098): 6.08e-80: 297: 22.88		GRIA2_HUMAN (1-849): 0: 826: 74.01
+	Mm
		434795 SPTA1_MOUSE (1-2472): 1.64e-151: 528: 54.16		NMDZ1_MOUSE (4-901): 0: 571: 22.65
+	Rn
		585221 SPTN2_RAT (1652-2340): 1.3e-22: 108: 19.24		GRIA4_RAT (1-902): 0: 911: 100.00
+	Rn
		585223 ACTN4_RAT (1843-2219): 2.81e-10: 68.2: 20.55		GRIA4_RAT (1-902): 0: 911: 100.00
+	Hs
		786728 SPTB2_HUMAN (1-521): 1.54e-19: 99: 31.55		GRIA2_HUMAN (1-849): 0: 826: 74.01
+	Hs
		984260 SPTN1_HUMAN (3-2098): 6.08e-80: 297: 22.88		NMDZ1_HUMAN (4-896): 0: 581: 22.46
+	Mm
		723587 SPTB2_MOUSE (1-521): 1.96e-19: 98.6: 31.55		NMDZ1_MOUSE (4-901): 0: 571: 22.65
+	Mm
		723613 ACTN2_MOUSE (1737-2210): 3.4e-13: 77.8: 21.48		NMDZ1_MOUSE (4-901): 0: 571: 22.65
+	Hs
		211568 ACTN4_HUMAN (1827-2219): 8.31e-10: 66.6: 20.86		NMDZ1_HUMAN (4-896): 0: 581: 22.46
+	Rn
		723638 ACTN1_RAT (1862-2210): 2.64e-11: 71.6: 22.51		NMDZ1_RAT (4-901): 0: 572: 22.55