HitPredict

Interactor 1: SPTN1 (P16086)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2472 Rn			1 810
+	Rn
		1144216 Q6XD99_RAT (1-521): 2.75e-19: 98.3: 31.74		UBC_RAT (1-810): 0: 1000: 100.00
+	Rn
		1144315 ACTN1_RAT (1862-2210): 2.64e-11: 71.6: 22.51		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		475789 PLEC_HUMAN (1-1272): 1.62e-38: 161: 9.94		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476576 MACF1_HUMAN (803-2418): 2.95e-27: 124: 10.15		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475644 CENPE_HUMAN (1690-2426): 5.15e-16: 87.4: 10.70		UBC_HUMAN (1-533): 0: 662: 99.81
+	Mm
		476672 CE290_MOUSE (1474-2406): 2.74e-15: 85.1: 8.43		UBB_MOUSE (533-801): 1.37e-108: 336: 92.94
+	Hs
		397956 SPTN1_HUMAN (3-2098): 6.08e-80: 297: 22.88		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Mm
		82746 B9EKJ1_MOUSE (3-1701): 3.42e-48: 193: 20.84		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		924144 CP250_HUMAN (1-1084): 1.84e-39: 164: 10.69		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		477041 PLEC_MOUSE (1-1313): 1.2e-40: 169: 12.79		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397977 PLEC_HUMAN (1-1272): 1.62e-38: 161: 9.94		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Hs
		475174 CP250_HUMAN (1-1084): 1.84e-39: 164: 10.69		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70
+	Mm
		476949 DYST_MOUSE (398-2374): 5.79e-31: 137: 9.78		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476860 ACTN1_MOUSE (1862-2210): 2.76e-10: 68.2: 21.99		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476728 ACTN4_MOUSE (1843-2219): 8.52e-10: 66.6: 20.30		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397748 ACTN1_HUMAN (1862-2210): 4.47e-11: 70.9: 22.25		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Hs
		211461 ACTN4_HUMAN (1827-2219): 8.31e-10: 66.6: 20.86		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69