HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: CTCF (P49711)
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)
Gene: CTCF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001673 - male germ cell nucleus GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 727
+	Hs
		391598 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CTCF_HUMAN (1-727): 0: 637: 100.00
+	Hs
		470299 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		CTCF_HUMAN (1-727): 0: 637: 100.00
+	Hs
		830970 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		CTCF_HUMAN (1-727): 0: 637: 100.00
+	Hs
		260799 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		CTCF_HUMAN (1-727): 0: 637: 100.00
+	Hs
		555558 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		ZN420_HUMAN (91-569): 0: 549: 23.83
+	Hs
		1087059 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		CTCFL_HUMAN (223-631): 3.01e-168: 500: 63.08