HitPredict

Interactor 1: VATB (P16140)
V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 57 kDa subunit) (Vacuolar proton pump subunit B)
Gene: VMA2

Interactor 2: VATD (P32610)
V-type proton ATPase subunit D (V-ATPase subunit D) (Vacuolar proton pump subunit D)
Gene: VMA8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

The method score is based on:

Property	Details
Experiments	16429126, 16554755, 37968396, 12220197
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATP-synt_D~ATP-synt_ab
Common GO terms	GO:0000139 - Golgi membrane GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0000329 - fungal-type vacuole membrane GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex and 5 others more... GO:0033176 - proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0048388 - endosomal lumen acidification GO:0061795 - Golgi lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	517
Sc

1	256

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024