HitPredict

Interactor 1: ITB4 (P16144)
Integrin beta-4 (GP150) (CD antigen CD104)
Gene: ITGB4

Interactor 2: CD151 (P48509)
CD151 antigen (GP27) (Membrane glycoprotein SFA-1) (Platelet-endothelial tetraspan antigen 3) (PETA-3) (Tetraspanin-24) (Tspan-24) (CD antigen CD151)
Gene: CD151

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 10811835
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005604 - basement membrane GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion and 1 others more... GO:0009986 - cell surface
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1822 Hs			1 253
+	Hs
		403820 ITB1_HUMAN (5-719): 0: 620: 34.57		CD151_HUMAN (1-253): 6.35e-74: 227: 100.00
+	Hs
		50293 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN11_HUMAN (1-253): 4.04e-73: 225: 56.13
+	Hs
		403847 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN5_HUMAN (3-250): 3e-63: 200: 23.40
+	Hs
		403813 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN7_HUMAN (13-253): 1.56e-61: 195: 29.92
+	Hs
		403744 ITB1_HUMAN (5-719): 0: 620: 34.57		CD63_HUMAN (8-250): 7.79e-58: 185: 26.75
+	Hs
		403839 ITB1_HUMAN (5-719): 0: 620: 34.57		CD81_HUMAN (9-250): 5.01e-54: 176: 23.70
+	Hs
		574512 ITB5_HUMAN (4-649): 0: 611: 34.97		CD81_HUMAN (9-250): 5.01e-54: 176: 23.70
+	Hs
		326008 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN15_HUMAN (15-250): 9.71e-50: 166: 23.39
+	Hs
		403784 ITB1_HUMAN (5-719): 0: 620: 34.57		CD9_HUMAN (9-251): 1.52e-49: 164: 29.44
+	Hs
		156129 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN4_HUMAN (8-248): 7.87e-47: 157: 31.54
+	Hs
		326265 ITB1_HUMAN (5-719): 0: 620: 34.57		TSN12_HUMAN (13-248): 3.56e-46: 157: 27.09
+	Hs
		888000 ROBO1_HUMAN (812-1526): 3.16e-38: 159: 10.33		CD81_HUMAN (9-250): 5.01e-54: 176: 23.70
+	Hs
		905517 SDK2_HUMAN (1101-1820): 3.83e-30: 133: 9.83		TSN5_HUMAN (3-250): 3e-63: 200: 23.40
+	Hs
		602297 ROBO1_HUMAN (812-1526): 3.16e-38: 159: 10.33		CD9_HUMAN (9-251): 1.52e-49: 164: 29.44
+	Hs
		490008 PTPRF_HUMAN (821-1296): 1.34e-26: 121: 14.86		TSN17_HUMAN (3-250): 8.82e-63: 199: 26.42
+	Hs
		326081 SDK2_HUMAN (1101-1820): 3.83e-30: 133: 9.83		TSN15_HUMAN (15-250): 9.71e-50: 166: 23.39
+	Hs
		489929 PTPRF_HUMAN (821-1296): 1.34e-26: 121: 14.86		CD81_HUMAN (9-250): 5.01e-54: 176: 23.70
+	Hs
		602263 SDK2_HUMAN (1101-1820): 3.83e-30: 133: 9.83		CD9_HUMAN (9-251): 1.52e-49: 164: 29.44
+	Hs
		489901 PTPRF_HUMAN (821-1296): 1.34e-26: 121: 14.86		CD9_HUMAN (9-251): 1.52e-49: 164: 29.44
+	Hs
		276300 ITB2_HUMAN (537-760): 1.13e-14: 81.7: 15.92		UPK1B_HUMAN (7-249): 1.88e-47: 159: 20.54