Protein: GEMI5
Gem-associated protein 5 (Gemin5)

Gene: GEMI5, GEMIN5
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q8TEQ6

Gene Ontology (top 5):
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1256689

DDX20
Probable ATP-dependent RNA helicase DDX20

8

14

Small-scale

0.970

High

1256695

STRAP
Serine-threonine kinase receptor-associated protein

3

18

High-throughput

0.871

High

1084845

SMN
Survival motor neuron protein

6

1

Small-scale

0.739

High

911908

RUXF
Small nuclear ribonucleoprotein F

4

10

Small-scale

0.702

High

442334

RU17
U1 small nuclear ribonucleoprotein 70 kDa

4

9

High-throughput

0.699

High

1256684

GAR1
H/ACA ribonucleoprotein complex subunit 1

4

1

High-throughput

0.699

High

134133

DDX3X
ATP-dependent RNA helicase DDX3X

1

9

High-throughput

0.691

High

908044

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.691

High

1029285

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

4

High-throughput

0.691

High

1256673

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

4

High-throughput

0.691

High

1256679

DDX21
Nucleolar RNA helicase 2

1

13

High-throughput

0.691

High

911697

RUXE
Small nuclear ribonucleoprotein E

3

2

Small-scale

0.678

High

912685

SMD3
Small nuclear ribonucleoprotein Sm D3

3

12

Small-scale

0.674

High

912520

SMD2
Small nuclear ribonucleoprotein Sm D2

3

3

Small-scale

0.670

High

453872

RU2A
U2 small nuclear ribonucleoprotein A'

3

7

High-throughput

0.667

High

850869

AK1D1
Aldo-keto reductase family 1 member D1

3

1

High-throughput

0.667

High

1202512

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

1

High-throughput

0.667

High

539067

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

4

Small-scale

0.662

High

912079

RUXG
Small nuclear ribonucleoprotein G

3

8

Small-scale

0.660

High

815276

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.656

High

884044

GEMI4
Gem-associated protein 4

3

0

Small-scale

0.638

High

441337

RU2B
U2 small nuclear ribonucleoprotein B''

2

11

High-throughput

0.628

High

927987

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

5

High-throughput

0.628

High

157755

GEMI2
Gem-associated protein 2

3

0

Small-scale

0.628

High

912336

SMD1
Small nuclear ribonucleoprotein Sm D1

2

12

Small-scale

0.624

High

182841

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.618

High

232944

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

5

High-throughput

0.618

High

331852

NSD2
Histone-lysine N-methyltransferase NSD2

1

8

Small-scale

0.618

High

827982

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

8

High-throughput

0.618

High

908865

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

10

High-throughput

0.618

High

1024380

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.618

High

1058255

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

13

Small-scale

0.618

High

1064517

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.618

High

1146653

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.618

High

1159204

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.618

High

1170956

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.618

High

1256658

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

Small-scale

0.618

High

1256672

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.618

High

1256678

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.618

High

1256690

FBW1B
F-box/WD repeat-containing protein 11

1

16

High-throughput

0.618

High

726949

FUS
RNA-binding protein FUS

2

12

High-throughput

0.611

High

1239464

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

0

High-throughput

0.602

High

1256675

GEMI7
Gem-associated protein 7

2

0

High-throughput

0.602

High

1256683

GEMI8
Gem-associated protein 8

2

0

High-throughput

0.602

High

1200515

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.586

High

1256649

GEMI6
Gem-associated protein 6

2

0

Small-scale

0.585

High

553265

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

651769

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

6

High-throughput

0.584

High

720991

RFA3
Replication protein A 14 kDa subunit

2

6

High-throughput

0.584

High

1067549

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.578

High

800813

MK08
Mitogen-activated protein kinase 8

1

6

Small-scale

0.578

High

800991

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

10

Small-scale

0.578

High

1256666

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

5

Small-scale

0.578

High

1153303

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

225006

ZNRD2
Protein ZNRD2

2

2

High-throughput

0.574

High

1256677

CPNE5
Copine-5

2

1

High-throughput

0.574

High

370071

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

408651

KPCB
Protein kinase C beta type

2

6

High-throughput

0.571

High

1234536

SH2D3
SH2 domain-containing protein 3C

2

3

High-throughput

0.571

High

1256668

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.553

High

417014

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.536

High

243519

DNJA2
DnaJ homolog subfamily A member 2

1

17

High-throughput

0.536

High

304259

UBR5
E3 ubiquitin-protein ligase UBR5

1

11

High-throughput

0.536

High

416666

S10A6
Protein S100-A6

1

2

High-throughput

0.536

High

418490

NPM
Nucleophosmin

1

7

High-throughput

0.536

High

446713

SNRPA
U1 small nuclear ribonucleoprotein A

1

9

High-throughput

0.536

High

448748

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

495576

THIO
Thioredoxin

1

5

High-throughput

0.536

High

508624

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

639615

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.536

High

647634

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.536

High

682904

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

20

High-throughput

0.536

High

708342

TTK
Dual specificity protein kinase TTK

1

5

High-throughput

0.536

High

719752

RADI
Radixin

1

4

High-throughput

0.536

High

826316

CDK8
Cyclin-dependent kinase 8

1

15

High-throughput

0.536

High

867453

ICLN
Methylosome subunit pICln

1

2

High-throughput

0.536

High

914551

ERF1
Eukaryotic peptide chain release factor subunit 1

1

3

High-throughput

0.536

High

996786

SSRP1
FACT complex subunit SSRP1

1

18

High-throughput

0.536

High

1034606

GOGA4
Golgin subfamily A member 4

1

11

High-throughput

0.536

High

1042123

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1054458

RBM39
RNA-binding protein 39

1

11

High-throughput

0.536

High

1069446

TEBP
Prostaglandin E synthase 3

1

5

High-throughput

0.536

High

1074187

SF3A1
Splicing factor 3A subunit 1

1

8

High-throughput

0.536

High

1076073

OASL
2'-5'-oligoadenylate synthase-like protein

1

10

High-throughput

0.536

High

1084541

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

15

High-throughput

0.536

High

1086378

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

1

High-throughput

0.536

High

1103194

PRIC4
Prickle-like protein 4

1

3

High-throughput

0.536

High

1151362

H2A2A
Histone H2A type 2-A

1

9

High-throughput

0.536

High

1256648

PDC6I
Programmed cell death 6-interacting protein

1

7

High-throughput

0.536

High

1256650

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1256657

FGF14
Fibroblast growth factor 14

1

2

High-throughput

0.536

High

1256659

CUL5
Cullin-5

1

20

High-throughput

0.536

High

1256660

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1256662

ARMC5
Armadillo repeat-containing protein 5

1

6

High-throughput

0.536

High

1256665

RBM14
RNA-binding protein 14

1

15

High-throughput

0.536

High

1256674

SYNCI
Syncoilin

1

12

High-throughput

0.536

High

1256676

CENPJ
Centromere protein J

1

6

High-throughput

0.536

High

1256687

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.536

High

717225

CTNB1
Catenin beta-1

1

7

Small-scale

0.515

High

340815

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.513

High

949205

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

0

High-throughput

0.513

High

1058193

LPIN1
Phosphatidate phosphatase LPIN1

1

0

High-throughput

0.513

High

1068219

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

1256686

SPN90
NCK-interacting protein with SH3 domain

1

0

High-throughput

0.513

High

1256693

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

1256697

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

833786

CLK1
Dual specificity protein kinase CLK1

1

13

High-throughput

0.501

High

902682

SUMO2
Small ubiquitin-related modifier 2

1

1

High-throughput

0.501

High

1256696

NPTN
Neuroplastin

1

3

High-throughput

0.489

High

165865

KDM6B
Lysine-specific demethylase 6B

1

17

Small-scale

0.479

High

217493

AIRE
Autoimmune regulator

1

13

Small-scale

0.479

High

228157

PRKN
E3 ubiquitin-protein ligase parkin

1

19

High-throughput

0.479

High

232369

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

244689

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

246011

PFD1
Prefoldin subunit 1

1

5

High-throughput

0.479

High

314882

FMNL1
Formin-like protein 1

1

1

Small-scale

0.479

High

322913

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.479

High

347412

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

387174

P53
Cellular tumor antigen p53

1

10

High-throughput

0.479

High

509693

UBL4A
Ubiquitin-like protein 4A

1

12

High-throughput

0.479

High

684913

STIP1
Stress-induced-phosphoprotein 1

1

12

High-throughput

0.479

High

718043

BMI1
Polycomb complex protein BMI-1

1

12

High-throughput

0.479

High

736610

RL4
Large ribosomal subunit protein uL4

1

5

High-throughput

0.479

High

749706

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

779789

CCNF
Cyclin-F

1

20

High-throughput

0.479

High

808793

YAP1
Transcriptional coactivator YAP1

1

11

High-throughput

0.479

High

824215

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

14

High-throughput

0.479

High

828844

SRP09
Signal recognition particle 9 kDa protein

1

1

Small-scale

0.479

High

894961

SRP54
Signal recognition particle subunit SRP54

1

3

Small-scale

0.479

High

941216

RNF4
E3 ubiquitin-protein ligase RNF4

1

7

High-throughput

0.479

High

1034944

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

12

High-throughput

0.479

High

1035918

BIRC3
Baculoviral IAP repeat-containing protein 3

1

8

High-throughput

0.479

High

1038567

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.479

High

1070567

RNPS1
RNA-binding protein with serine-rich domain 1

1

11

High-throughput

0.479

High

1116410

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1136190

RC3H1
Roquin-1

1

3

High-throughput

0.479

High

1148687

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1188604

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1205104

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

10

Small-scale

0.479

High

1206001

MIB1
E3 ubiquitin-protein ligase MIB1

1

4

High-throughput

0.479

High

1236392

SIR6
NAD-dependent protein deacylase sirtuin-6

1

11

High-throughput

0.479

High

1255625

RBCC1
RB1-inducible coiled-coil protein 1

1

16

High-throughput

0.479

High

1256651

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1256652

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1256653

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1256654

RBP56
TATA-binding protein-associated factor 2N

1

9

High-throughput

0.479

High

1256655

CSN5
COP9 signalosome complex subunit 5

1

7

High-throughput

0.479

High

1256656

FGF11
Fibroblast growth factor 11

1

2

High-throughput

0.479

High

1256664

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1256667

BARD1
BRCA1-associated RING domain protein 1

1

5

High-throughput

0.479

High

1256669

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1256670

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

High-throughput

0.479

High

1256671

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

1256680

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

1256682

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

1256685

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.479

High

1256688

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1256691

RCOR1
REST corepressor 1

1

13

High-throughput

0.479

High

1115736

CRY2
Cryptochrome-2

1

0

High-throughput

0.458

High

1256661

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1256681

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

68437

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

8

High-throughput

0.445

High

91325

E5RGS4
Prefoldin subunit 1

1

5

High-throughput

0.445

High

374586

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.445

High

402273

JUN
Transcription factor Jun

1

13

High-throughput

0.445

High

998131

NCBP1
Nuclear cap-binding protein subunit 1

1

1

High-throughput

0.445

High

1057557

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

9

High-throughput

0.445

High

1130365

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

1137385

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

6

Small-scale

0.445

High

1256692

AKP8L
A-kinase anchor protein 8-like

1

3

High-throughput

0.445

High

385218

NTRK1
High affinity nerve growth factor receptor

1

16

High-throughput

0.437

High

879458

UCP3
Putative mitochondrial transporter UCP3

1

6

Small-scale

0.437

High

1166844

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.437

High

1256694

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

1101862

S35G1
Solute carrier family 35 member G1

1

0

High-throughput

0.279

Low

1256663

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1255998

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

1088

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024