Protein: NDRG1
Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42)

Gene: NDRG1
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q92597

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1365193

NDRG2
Protein NDRG2

3

0

High-throughput

0.816

High

1049631

1433F
14-3-3 protein eta

3

1

High-throughput

0.667

High

420641

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

3

3

Small-scale

0.662

High

631383

RAB5A
Ras-related protein Rab-5A

3

1

High-throughput

0.633

High

124676

PLM
Phospholemman

2

5

High-throughput

0.628

High

326441

S1PR2
Sphingosine 1-phosphate receptor 2

2

1

High-throughput

0.628

High

1365172

CDK15
Cyclin-dependent kinase 15

2

1

High-throughput

0.628

High

966692

1433G
14-3-3 protein gamma

2

1

High-throughput

0.621

High

556253

CADH1
Cadherin-1

2

1

Small-scale

0.611

High

1365185

SHCAF
SIN3-HDAC complex-associated factor

2

0

High-throughput

0.602

High

1217983

MYOME
Myomegalin

2

0

High-throughput

0.585

High

242457

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

375789

RASK
GTPase KRas

2

9

High-throughput

0.584

High

630915

RAB4A
Ras-related protein Rab-4A

2

2

Small-scale

0.584

High

978204

RHOB
Rho-related GTP-binding protein RhoB

2

3

High-throughput

0.584

High

461770

HS90A
Heat shock protein HSP 90-alpha

2

0

Small-scale

0.576

High

934931

TERA
Transitional endoplasmic reticulum ATPase

2

0

Small-scale

0.576

High

1327773

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.571

High

372718

MYC
Myc proto-oncogene protein

2

0

Small-scale

0.569

High

652550

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

1

Small-scale

0.561

High

891704

GSK3B
Glycogen synthase kinase-3 beta

1

1

Small-scale

0.561

High

540596

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.559

High

976461

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.559

High

436709

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

886299

ARL4D
ADP-ribosylation factor-like protein 4D

1

3

High-throughput

0.541

High

219648

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.537

High

274686

DNJB6
DnaJ homolog subfamily B member 6

1

2

High-throughput

0.536

High

420826

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

4

High-throughput

0.536

High

733407

CCR1
C-C chemokine receptor type 1

1

4

High-throughput

0.536

High

764927

CTNB1
Catenin beta-1

1

1

Small-scale

0.536

High

931423

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

4

High-throughput

0.536

High

943106

STX17
Syntaxin-17

1

1

High-throughput

0.536

High

1010764

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.536

High

1023848

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.536

High

1132568

FXYD3
FXYD domain-containing ion transport regulator 3

1

5

High-throughput

0.536

High

1365176

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.536

High

1365188

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1365196

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.536

High

578310

ETS2
Protein C-ets-2

1

0

High-throughput

0.518

High

1364758

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.518

High

358762

LDHA
L-lactate dehydrogenase A chain

1

1

Small-scale

0.515

High

535360

BIP
Endoplasmic reticulum chaperone BiP

1

4

Small-scale

0.515

High

550386

PABP1
Polyadenylate-binding protein 1

1

1

Small-scale

0.515

High

552336

ADT3
ADP/ATP translocase 3

1

1

Small-scale

0.515

High

610424

PRS6A
26S proteasome regulatory subunit 6A

1

2

Small-scale

0.515

High

620499

NUCL
Nucleolin

1

1

Small-scale

0.515

High

729378

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

Small-scale

0.515

High

906438

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

Small-scale

0.515

High

912987

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

3

Small-scale

0.515

High

991075

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

3

Small-scale

0.515

High

1027632

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

Small-scale

0.515

High

1363283

DDX1
ATP-dependent RNA helicase DDX1

1

2

Small-scale

0.515

High

1365166

AP2M1
AP-2 complex subunit mu

1

1

Small-scale

0.515

High

1365201

AP1M2
AP-1 complex subunit mu-2

1

1

Small-scale

0.515

High

1252760

RN111
E3 ubiquitin-protein ligase Arkadia

1

1

High-throughput

0.515

High

1365179

LDH6B
L-lactate dehydrogenase A-like 6B

1

1

High-throughput

0.515

High

287463

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

0

High-throughput

0.513

High

602822

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

611933

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

961200

FGF12
Fibroblast growth factor 12

1

0

High-throughput

0.513

High

1025220

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.513

High

1031830

LAT1
Large neutral amino acids transporter small subunit 1

1

0

High-throughput

0.513

High

1063486

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.513

High

1295633

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.513

High

1365163

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

1365165

OPTN
Optineurin

1

0

High-throughput

0.513

High

1365168

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.513

High

1365174

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1365177

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1365186

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

1365195

NTNG1
Netrin-G1

1

0

High-throughput

0.513

High

1365200

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.513

High

387303

APOA1
Apolipoprotein A-I

1

0

Small-scale

0.504

High

122966

SGK1
Serine/threonine-protein kinase Sgk1

1

2

Small-scale

0.501

High

339550

ACSL3
Fatty acid CoA ligase Acsl3

1

0

Small-scale

0.493

High

470324

NEP
Neprilysin

1

0

Small-scale

0.493

High

558299

XRCC6
X-ray repair cross-complementing protein 6

1

0

Small-scale

0.493

High

565992

EF2
Elongation factor 2

1

0

Small-scale

0.493

High

573191

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.493

High

576809

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

0

Small-scale

0.493

High

608678

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

Small-scale

0.493

High

638132

AOFA
Amine oxidase [flavin-containing] A

1

0

Small-scale

0.493

High

658308

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.493

High

687703

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

0

Small-scale

0.493

High

688089

EF1G
Elongation factor 1-gamma

1

0

Small-scale

0.493

High

698961

CALX
Calnexin

1

0

Small-scale

0.493

High

749975

KINH
Kinesin-1 heavy chain

1

0

Small-scale

0.493

High

760975

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

Small-scale

0.493

High

773586

COPB2
Coatomer subunit beta'

1

0

Small-scale

0.493

High

778743

PRS7
26S proteasome regulatory subunit 7

1

0

Small-scale

0.493

High

785333

RL4
Large ribosomal subunit protein uL4

1

0

Small-scale

0.493

High

788121

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

Small-scale

0.493

High

810254

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.493

High

832094

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

0

Small-scale

0.493

High

860295

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.493

High

881261

FAS
Fatty acid synthase

1

0

Small-scale

0.493

High

949409

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

Small-scale

0.493

High

954210

RS20
Small ribosomal subunit protein uS10

1

0

Small-scale

0.493

High

969341

RS8
Small ribosomal subunit protein eS8

1

0

Small-scale

0.493

High

970007

RS16
Small ribosomal subunit protein uS9

1

0

Small-scale

0.493

High

979106

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.493

High

983181

RS26
Small ribosomal subunit protein eS26

1

0

Small-scale

0.493

High

993274

ACTG
Actin, cytoplasmic 2

1

0

Small-scale

0.493

High

1013826

RL24
Large ribosomal subunit protein eL24

1

0

Small-scale

0.493

High

1026154

CLH1
Clathrin heavy chain 1

1

0

Small-scale

0.493

High

1033100

EWS
RNA-binding protein EWS

1

0

Small-scale

0.493

High

1048051

TLE3
Transducin-like enhancer protein 3

1

0

Small-scale

0.493

High

1089771

ILF3
Interleukin enhancer-binding factor 3

1

0

Small-scale

0.493

High

1098077

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.493

High

1137425

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

1148920

SC23A
Protein transport protein Sec23A

1

0

Small-scale

0.493

High

1365162

RENT1
Regulator of nonsense transcripts 1

1

0

Small-scale

0.493

High

1365167

CNDP2
Cytosolic non-specific dipeptidase

1

0

Small-scale

0.493

High

1365194

RUVB2
RuvB-like 2

1

0

Small-scale

0.493

High

282283

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.493

High

1187846

FX4L6
Forkhead box protein D4-like 6

1

0

High-throughput

0.493

High

1307987

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.493

High

1326015

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.493

High

1365170

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.493

High

1365173

SPAG8
Sperm-associated antigen 8

1

0

High-throughput

0.493

High

1365180

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.493

High

1365182

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.493

High

1365183

DCR1B
5' exonuclease Apollo

1

0

High-throughput

0.493

High

1365198

MSRB2
Methionine-R-sulfoxide reductase B2, mitochondrial

1

0

High-throughput

0.493

High

1365199

KAD6
Adenylate kinase isoenzyme 6

1

0

High-throughput

0.493

High

325341

OR2A4
Olfactory receptor 2A4

1

1

High-throughput

0.489

High

1315969

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

827455

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.486

High

387546

APOA2
Apolipoprotein A-II

1

0

Small-scale

0.480

High

189752

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

374103

RASN
GTPase NRas

1

9

High-throughput

0.479

High

374820

RASH
GTPase HRas

1

6

High-throughput

0.479

High

520237

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

589295

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

601392

RHOQ
Rho-related GTP-binding protein RhoQ

1

4

High-throughput

0.479

High

696083

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

761792

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

862334

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

901977

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

953597

RAC3
Ras-related C3 botulinum toxin substrate 3

1

3

High-throughput

0.479

High

956429

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

986604

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

1015644

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

1041206

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1087225

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1104236

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1112936

CUL2
Cullin-2

1

1

Small-scale

0.479

High

1114971

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

1145044

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1218978

TET5C
Terminal nucleotidyltransferase 5C

1

2

High-throughput

0.479

High

1254870

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1365181

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.479

High

1365184

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.479

High

1365192

PRAF1
Prenylated Rab acceptor protein 1

1

4

Small-scale

0.479

High

1244708

TTC33
Tetratricopeptide repeat protein 33

1

1

High-throughput

0.470

High

1159317

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.460

High

218561

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

226156

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

285388

EED
Polycomb protein EED

1

0

High-throughput

0.458

High

327388

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

401226

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

407673

S100B
Protein S100-B

1

0

Small-scale

0.458

High

463687

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

582905

EZRI
Ezrin

1

0

High-throughput

0.458

High

606954

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

613117

EGR1
Early growth response protein 1

1

0

Small-scale

0.458

High

641642

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

0

Small-scale

0.458

High

642998

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

715698

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

845741

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

884842

PPM1F
Protein phosphatase 1F

1

0

Small-scale

0.458

High

941506

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.458

High

970858

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

975158

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1098305

TBX2
T-box transcription factor TBX2

1

0

Small-scale

0.458

High

1101863

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

1159781

OCLN
Occludin

1

0

High-throughput

0.458

High

1233392

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1289496

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1332687

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.458

High

1361987

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

1364479

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1365164

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1365171

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

1365191

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

369193

OAS1
2'-5'-oligoadenylate synthase 1

1

1

High-throughput

0.445

High

565677

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

High-throughput

0.445

High

609764

LEG3
Galectin-3

1

1

High-throughput

0.445

High

1315697

DND1
Dead end protein homolog 1

1

1

High-throughput

0.445

High

1365189

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.445

High

1163595

RTN1
Reticulon-1

1

3

Small-scale

0.439

High

106374

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

768780

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

127150

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

967163

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.426

High

1365175

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.426

High

1365178

PCGF6
Polycomb group RING finger protein 6

1

0

High-throughput

0.426

High

1104034

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

1365169

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

3

High-throughput

0.407

High

1013316

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1043643

COAA1

1

0

High-throughput

0.279

Low

1306977

CERS3
Ceramide synthase 3

1

0

High-throughput

0.279

Low

1328463

CMIP6
Ciliary microtubule inner protein 6

1

0

High-throughput

0.279

Low

1365187

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low

1365197

WASC3
WASH complex subunit 3

1

0

High-throughput

0.279

Low

418320

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

Small-scale

0.269

Low

1293097

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1089

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

1365190

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025