HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Hs			1 156
+	Hs
		557061 PGFRA_HUMAN (1-1089): 0: 817: 100.00		CDN2B_HUMAN (3-136): 4.71e-52: 163: 81.34
+	Hs
		557108 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		557062 PGFRA_HUMAN (1-1089): 0: 817: 100.00		CDN2C_HUMAN (21-135): 1.37e-25: 97.4: 28.21
+	Hs
		557289 PGFRA_HUMAN (1-1089): 0: 817: 100.00		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		474791 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		POTEI_HUMAN (49-152): 1.58e-18: 83.1: 13.89
+	Hs
		1083910 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59
+	Hs
		607908 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		607909 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2B_HUMAN (3-136): 4.71e-52: 163: 81.34
+	Hs
		1083907 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		601612 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		434183 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		608197 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		ANR26_HUMAN (2-155): 9.25e-33: 123: 18.59
+	Hs
		507954 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		507971 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		507831 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK1_HUMAN (2-130): 2.4e-33: 125: 24.62
+	Hs
		607910 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2C_HUMAN (21-135): 1.37e-25: 97.4: 28.21
+	Hs
		608115 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		TANC1_HUMAN (56-154): 1.3e-14: 71.9: 21.00
+	Hs
		608184 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		674564 UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		427015 CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48